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      Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023)

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          Abstract

          Targeted LNPs Delivery to the Bone Marrow

          In article number 2301377, Dana Tarab‐Ravski, Dan Peer, and co‐workers develop targeted lipid nanoparticles to efficiently deliver therapeutic RNA to multiple myeloma cells in the bone marrow. In a novel xenograft multiple myeloma (MM) mouse model, this delivery system demonstrates its ability to specifically target MM cells and produce a positive clinical outcome in mice engrafted with MM.

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          Journal
          Journal ID (nlm-ta): Adv Sci (Weinh)
          Journal ID (iso-abbrev): Adv Sci (Weinh)
          Journal ID (doi): 10.1002/(ISSN)2198-3844
          Journal ID (publisher-id): ADVS
          Title: Advanced Science
          Publisher: John Wiley and Sons Inc. (Hoboken )
          ISSN (Electronic): 2198-3844
          Publication date (Electronic): 27 July 2023
          Publication date Collection: July 2023
          Volume: 10
          Issue: 21 ( doiID: 10.1002/advs.v10.21 )
          Electronic Location Identifier: 2370141
          Article
          Publisher ID: ADVS202370141
          DOI: 10.1002/advs.202370141
          PMC ID: 10375169
          SO-VID: 4f5f2d23-904c-4726-9872-85d4cee765e8
          Copyright © © 2023 Wiley‐VCH GmbH
          License:

          This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

          History
          Page count
          Figures: 1, Tables: 0, Pages: 1, Words: 238
          Categories
          Subject: Inside Back Cover
          Subject: Inside Back Cover
          Custom metadata
          source-schema-version-number 2.0
          cover-date July 27, 2023
          details-of-publishers-convertor Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.2 mode:remove_FC converted:28.07.2023

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