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      Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate cyclophosphamide-induced ongoing bladder overactivity and acidic adenosine triphosphate solution-induced hyperactivity on rats prestimulated bladder.

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          Abstract

          Ba-Wei-Die-Huang-Wan (BWDHW) is the traditional Chinese medicine formula containing eight ingredients, namely Rehmannia glutinosa (Gaetn.) DC., root, steamed & dried; Cornus officinalis Siebold & Zucc., fructus, dried; Dioscorea oppositifolia L., root, dried; Alisma plantago-aquatica, subsp. orientale (Sam.) Sam., tuber, dried; Poria cocos (Fr.) Wolf., sclerotium, dried; Paeonia×suffruticosa Andrews, bark, dried; Cinnamomum cassia (Nees & T.Nees) J. Presl, bark, dried; Aconitum carmichaeli Debeaux, lateral root, dried & processed. It has been used for diabetes and urinary frequency treatments.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J Ethnopharmacol
          Title: Journal of ethnopharmacology
          Publisher: Elsevier BV
          ISSN (Electronic): 1872-7573
          ISSN (Print): 0378-8741
          Publication date (Electronic): May 26 2016
          Volume: 184
          Affiliations
          [1 ] Division of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: dinor666@ms32.hinet.net.
          [2 ] Department of International Business, College of Commerce and Management, Cheng Shiu University, Kaohsiung, Taiwan. Electronic address: angelawu1974@yahoo.com.tw.
          [3 ] Division of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: chuang82@ms26.hinet.net.
          [4 ] Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: tainyl@hotmail.com.
          [5 ] Division of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: cphtem@yahoo.com.tw.
          Article
          Publisher Item ID: S0378-8741(15)30277-4
          DOI: 10.1016/j.jep.2015.12.026
          PubMed ID: 26719284
          SO-VID: 4f3e3729-c880-4a26-9549-41b427bd43d1
          History

          Keywords: Muscarinic receptors,Hachimi-jio-gan,Cinnamic acid (PubChem CID: 444539),Cinnamaldehyde (PubChem CID: 637511),Ba-Wei-Die-Huang-Wan,5-Hydroxymethylfurfural (PubChem CID: 237332),TRPV1 receptor,Paeonol (PubChem CID: 11092),Paeoniflorin (PubChem CID: 442534),P2X receptor,Overactive bladder,Loganin (PubChem CID: 87691)
          Data availability:
          Keywords: Muscarinic receptors, Hachimi-jio-gan, Cinnamic acid (PubChem CID: 444539), Cinnamaldehyde (PubChem CID: 637511), Ba-Wei-Die-Huang-Wan, 5-Hydroxymethylfurfural (PubChem CID: 237332), TRPV1 receptor, Paeonol (PubChem CID: 11092), Paeoniflorin (PubChem CID: 442534), P2X receptor, Overactive bladder, Loganin (PubChem CID: 87691)

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