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      Assessing the risk of metabolic syndrome and diabetes in relation to Hookah smoking: Evidence from a cohort study in Southern Iran

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          Abstract

          Background

          Hookah smoking has pointedly increased worldwide and could have different harmful health effects. However, long term hookah smoking effects on chronic diseases has not been well studied. This study was aimed to investigate the relationship between hookah smoking with metabolic syndrome and diabetes.

          Methods

          In this prospective study, the baseline data from 3695 participant (35−70 years old) of Bandar‐e‐Kong cohort study in Hormozgan province, Iran were used. In this study, data were collected through the questionnaires designed in the Kong cohort study and 25  mm of blood sample. All analyses were performed using SPSS version 27.0 and the ggplot2 package in RStudio version 2023.06.1 + 524. p < 0.05 was considered a significant difference.

          Results

          The prevalence of hookah smoking was 17.3% in total. Also, the prevalence of metabolic syndrome, diabetes, hypertension, and dyslipidemia were 35.6, 15.2, 31.2, and 78.0%, respectively. Our results showed that there were statistically significant relationship between hookah smoking and metabolic syndrome, hypertension and diabetes ( p < 0.05). In the case of dyslipidemia, hookah smoking was also associated with increase in dyslipidemia ( p < 0.05).

          Conclusions

          More evidence is needed to understand the mechanism of hookah smoking and these health effects. As well as, health education and increasing public awareness about the health effects of hookah smoking and implementation of smoking prohibition policies are highly recommended.

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          Most cited references48

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          Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design.

          Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study-Prospective Epidemiological Research Studies in Iran (PERSIAN)-in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge.
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            Smoking and the risk of type 2 diabetes.

            Despite accumulating evidence demonstrating strong epidemiologic and mechanistic associations between cigarette smoking, hyperglycemia, and the development of type 2 diabetes, tobacco abuse has not been uniformly recognized as a modifiable risk factor in diabetes prevention or screening strategies. In this review, we highlight population-based studies that have linked cigarette smoking with an increased risk of type 2 diabetes and summarize clinical and preclinical studies offering insight into mechanisms through which cigarette smoking and nicotine exposure impact body composition, insulin sensitivity, and pancreatic β cell function. Key questions for future studies are identified and strategies for smoking cessation as a means to decrease diabetes risk are discussed.
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              Waterpipe smoking and cancer: systematic review and meta-analysis.

              Although accumulating evidence suggests harmful effects of waterpipe smoking, there is limited information about its direct association with chronic diseases, notably cancer. We provide an up-to-date systematic review and meta-analysis of the association between waterpipe smoking and cancer.
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                Author and article information

                Contributors
                mdadipoor@yahoo.com
                Journal
                Health Sci Rep
                Health Sci Rep
                10.1002/(ISSN)2398-8835
                HSR2
                Health Science Reports
                John Wiley and Sons Inc. (Hoboken )
                2398-8835
                22 April 2024
                April 2024
                : 7
                : 4 ( doiID: 10.1002/hsr2.v7.4 )
                : e1996
                Affiliations
                [ 1 ] Social Determinants in Health Promotion Research Centre, Hormozgan Health Institute Hormozgan University of Medical Sciences Bandar Abbas Iran
                [ 2 ] Tobacco and Health Research Centre Hormozgan University of Medical Sciences Bandar Abbas Iran
                [ 3 ] Biostatistics and Epidemiology Department, Faculty of Health Mazandaran University of Medical Sciences Sari Iran
                [ 4 ] Department of Health Services, School of Public Health Iran University of Medical Sciences Tehran Iran
                Author notes
                [*] [* ] Correspondence Sara Dadipoor, Tobacco and Health research center, Hormozgan university of medical sciences, Bandar abbas, Iran.

                Email: mdadipoor@ 123456yahoo.com

                Author information
                http://orcid.org/0000-0003-0512-9033
                http://orcid.org/0000-0002-4205-6235
                Article
                HSR21996
                10.1002/hsr2.1996
                11035749
                38655419
                4cad0ded-d4f3-4088-ab89-7b13119fd94b
                © 2024 The Authors. Health Science Reports published by Wiley Periodicals LLC.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 25 November 2023
                : 14 October 2023
                : 07 March 2024
                Page count
                Figures: 2, Tables: 5, Pages: 12, Words: 6050
                Funding
                Funded by: Hormozgan University of Medical Sciences , doi 10.13039/501100011917;
                Categories
                Original Research
                Original Research
                Custom metadata
                2.0
                April 2024
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.4.0 mode:remove_FC converted:23.04.2024

                bandar‐e‐kong cohort study,diabetes,hookah smoking,metabolic syndrome

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