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      COVID‐19 vaccine hesitancy: Race/ethnicity, trust, and fear

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          Abstract

          Understanding and minimizing coronavirus disease 2019 (COVID‐19) vaccine hesitancy is critical to population health and minimizing health inequities, which continue to be brought into stark relief by the pandemic. We investigate questions regarding vaccine hesitancy in a sample ( n = 1205) of Arkansas adults surveyed online in July/August of 2020. We examine relationships among sociodemographics, COVID‐19 health literacy, fear of COVID‐19 infection, general trust in vaccines, and COVID‐19 vaccine hesitancy using bivariate analysis and a full information maximum likelihood (FIML) logistic regression model. One in five people (21,21.86%) reported hesitancy to take a COVID‐19 vaccine. Prevalence of COVID‐19 vaccine hesitancy was highest among Black/African Americans (50.00%), respondents with household income less than $25K (30.68%), some college (32.17%), little to no fear of infection from COVID‐19 (62.50%), and low trust in vaccines in general (55.84%). Odds of COVID‐19 vaccine hesitancy were 2.42 greater for Black/African American respondents compared to White respondents ( p < 0.001), 1.67 greater for respondents with some college/technical degree compared to respondents with a 4‐year degree ( p < 0.05), 5.48 greater for respondents with no fear of COVID‐19 infection compared to those who fear infection to a great extent ( p < 0.001), and 11.32 greater for respondents with low trust in vaccines ( p < 0.001). Sociodemographic differences in COVID‐19 vaccine hesitancy raise concerns about the potential of vaccine implementation to widen existing health disparities in COVID‐19 related infections, particularly among Black/African Americans. Fear of infection and general mistrust in vaccines are significantly associated with vaccine hesitancy.

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          Most cited references34

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          Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

          Research electronic data capture (REDCap) is a novel workflow methodology and software solution designed for rapid development and deployment of electronic data capture tools to support clinical and translational research. We present: (1) a brief description of the REDCap metadata-driven software toolset; (2) detail concerning the capture and use of study-related metadata from scientific research teams; (3) measures of impact for REDCap; (4) details concerning a consortium network of domestic and international institutions collaborating on the project; and (5) strengths and limitations of the REDCap system. REDCap is currently supporting 286 translational research projects in a growing collaborative network including 27 active partner institutions.
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            Vaccine hesitancy: Definition, scope and determinants.

            The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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              COVID-19 and African Americans

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                Author and article information

                Contributors
                pamcelfish@uams.edu
                Journal
                Clin Transl Sci
                Clin Transl Sci
                10.1111/(ISSN)1752-8062
                CTS
                Clinical and Translational Science
                John Wiley and Sons Inc. (Hoboken )
                1752-8054
                1752-8062
                02 July 2021
                02 July 2021
                : 10.1111/cts.13077
                Affiliations
                [ 1 ] College of Medicine University of Arkansas for Medical Sciences Northwest Fayetteville Arkansas USA
                [ 2 ] Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock Arkansas USA
                [ 3 ] College of Pharmacy University of Arkansas for Medical Sciences Little Rock Arkansas USA
                Author notes
                [*] [* ] Correspondence

                Pearl A. McElfish, College of Medicine, University of Arkansas for Medical Sciences Northwest, 1125 N. College Ave., Fayetteville, AR 72703, USA.

                Email: pamcelfish@ 123456uams.edu

                Author information
                https://orcid.org/0000-0001-6809-892X
                https://orcid.org/0000-0002-0574-7790
                https://orcid.org/0000-0002-4033-6241
                Article
                CTS13077
                10.1111/cts.13077
                8444681
                34213073
                490c7bc6-8bc1-43ca-b386-365d0ab4309a
                © 2021 The Authors. Clinical and Translational Science published by Wiley Periodicals LLC on behalf of the American Society for Clinical Pharmacology and Therapeutics.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 02 April 2021
                : 26 February 2021
                : 30 April 2021
                Page count
                Figures: 0, Tables: 3, Pages: 8, Words: 10375
                Funding
                Funded by: Translational Research Institute (TRI)
                Award ID: UL1 TR003107
                Funded by: National Center for Advancing Translational Sciences , doi 10.13039/100006108;
                Funded by: National Institutes of Health (NIH) , doi 10.13039/100000002;
                Funded by: University of Arkansas for Medical Sciences (UAMS) , doi 10.13039/100008519;
                Award ID: IRB#261226
                Categories
                Article
                Research
                Custom metadata
                2.0
                corrected-proof
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.0.7 mode:remove_FC converted:16.09.2021

                Medicine
                Medicine

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