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      Realizing the Potential of Social Determinants Data: A Scoping Review of Approaches for Screening, Linkage, Extraction, Analysis and Interventions

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          Abstract

          Background

          Social determinants of health (SDoH) like socioeconomics and neighborhoods strongly influence outcomes, yet standardized SDoH data is lacking in electronic health records (EHR), limiting research and care quality.

          Methods

          We searched PubMed using keywords “SDOH” and “EHR”, underwent title/abstract and full-text screening. Included records were analyzed under five domains: 1) SDoH screening and assessment approaches, 2) SDoH data collection and documentation, 3) Use of natural language processing (NLP) for extracting SDoH, 4) SDoH data and health outcomes, and 5) SDoH-driven interventions.

          Results

          We identified 685 articles, of which 324 underwent full review. Key findings include tailored screening instruments implemented across settings, census and claims data linkage providing contextual SDoH profiles, rule-based and neural network systems extracting SDoH from notes using NLP, connections found between SDoH data and healthcare utilization/chronic disease control, and integrated care management programs executed. However, considerable variability persists across data sources, tools, and outcomes.

          Discussion

          Despite progress identifying patient social needs, further development of standards, predictive models, and coordinated interventions is critical to fulfill the potential of SDoH-EHR integration. Additional database searches could strengthen this scoping review. Ultimately widespread capture, analysis, and translation of multidimensional SDoH data into clinical care is essential for promoting health equity.

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          Most cited references244

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          PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

          Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence on a topic and identify main concepts, theories, sources, and knowledge gaps. Although more scoping reviews are being done, their methodological and reporting quality need improvement. This document presents the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) checklist and explanation. The checklist was developed by a 24-member expert panel and 2 research leads following published guidance from the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network. The final checklist contains 20 essential reporting items and 2 optional items. The authors provide a rationale and an example of good reporting for each item. The intent of the PRISMA-ScR is to help readers (including researchers, publishers, commissioners, policymakers, health care providers, guideline developers, and patients or consumers) develop a greater understanding of relevant terminology, core concepts, and key items to report for scoping reviews.
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            County Health Rankings: Relationships Between Determinant Factors and Health Outcomes.

            The County Health Rankings (CHR) provides data for nearly every county in the U.S. on four modifiable groups of health factors, including healthy behaviors, clinical care, physical environment, and socioeconomic conditions, and on health outcomes such as length and quality of life. The purpose of this study was to empirically estimate the strength of association between these health factors and health outcomes and to describe the performance of the CHR model factor weightings by state.
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              Social determinants of health inequalities

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                Author and article information

                Journal
                medRxiv
                MEDRXIV
                medRxiv
                Cold Spring Harbor Laboratory
                06 February 2024
                : 2024.02.04.24302242
                Affiliations
                [1 ]University of Pittsburgh School of Medicine Department of Biomedical Informatics
                [2 ]University of Pennsylvania, Institute for Biomedical Informatics
                [3 ]University of Toronto, Institute of Health Policy Management and Evaluations
                [4 ]Duke-NUS Medical School, Centre for Quantitative Medicine
                [5 ]University of Pennsylvania, Department of Psychiatry
                [6 ]Cedars-Sinai Medical Center, Department of Computational Biomedicine
                [7 ]Northwestern University, Kellogg School of Management
                [8 ]University of Pennsylvania, Department of Biostatistics, Epidemiology and Informatics
                Author notes

                Contributorship Statement

                M.J.B. C.L., and D.L.M: Conceptualized the study design and methodology.

                C.L., D.L.M., X.M., S.H, and M.J.B.: Led data synthesis and analysis as well as initial manuscript drafting.

                C.L., R.Y., S.H., D.L.M., U.V., H.K.D., and P.F.: Contributed to metadata extraction from selected articles.

                C.L., Z.A. and H.K.D.: Developed visualizations and tables to summarize key data.

                All authors contributed intellectually to the interpretation of findings, critically revised the manuscript, gave final approval of the version to be published, and agree to be accountable for the work.

                Corresponding Author: Michael J. Becich, becich@ 123456pitt.edu , +1 (412) 606 6453, University of Pittsburgh, School of Medicine, Department of Biomedical Informatics, 5607 Baum Blvd, Pittsburgh, PA, USA, 15206
                Author information
                http://orcid.org/0000-0001-7434-6571
                http://orcid.org/0000-0003-3802-4457
                http://orcid.org/0000-0002-4165-3062
                http://orcid.org/0009-0006-0597-7197
                http://orcid.org/0000-0001-6021-4316
                http://orcid.org/0000-0003-3851-9521
                http://orcid.org/0000-0002-5633-1488
                http://orcid.org/0000-0002-4113-0616
                http://orcid.org/0000-0002-2136-3754
                http://orcid.org/0000-0001-7283-1653
                http://orcid.org/0000-0001-8658-9802
                http://orcid.org/0000-0003-0660-5230
                http://orcid.org/0000-0001-5998-8074
                Article
                10.1101/2024.02.04.24302242
                10871446
                38370703
                48afc855-0cac-4d4d-afd4-3646a5d69c7b

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.

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                Categories
                Article

                social determinants of health,electronic health records,health equity,natural language processing,social risk factors

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