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      Recent advances in metal–organic framework-based photoelectrochemical and electrochemiluminescence biosensors

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          Abstract

          This review summarizes recent advances on metal-organic frameworks for the applications in photoelectrochemical and electrochemiluminescence biosensors.

          Abstract

          As a newly emerging class of molecular crystal materials, metal–organic frameworks (MOFs) are extensively used in a variety of fields including catalysis, separation, energy storage, and biosensors, by virtue of their large specific surface area, excellent chemical stability, and adjustable pore size. In particular, several functional materials have been integrated into the MOF structure, which greatly improves the conductivity of MOFs and facilitates the application of MOFs in the field of electrochemical biosensing. Herein, this review highlights the recent applications of MOF composites for photoelectrochemical (PEC) and electrochemiluminescence (ECL) biosensors. This paper first briefly describes the classification and various synthesis methods of MOFs. Then, it comprehensively summarizes different types of MOF-based biosensors in PEC and ECL and their applications. Finally, the challenges and outlook for future work in MOF-based PEC and ECL biosensors are tentatively proposed.

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          Most cited references163

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          The chemistry and applications of metal-organic frameworks.

          Crystalline metal-organic frameworks (MOFs) are formed by reticular synthesis, which creates strong bonds between inorganic and organic units. Careful selection of MOF constituents can yield crystals of ultrahigh porosity and high thermal and chemical stability. These characteristics allow the interior of MOFs to be chemically altered for use in gas separation, gas storage, and catalysis, among other applications. The precision commonly exercised in their chemical modification and the ability to expand their metrics without changing the underlying topology have not been achieved with other solids. MOFs whose chemical composition and shape of building units can be multiply varied within a particular structure already exist and may lead to materials that offer a synergistic combination of properties.
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            Design and synthesis of an exceptionally stable and highly porous metal-organic framework

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              A new zirconium inorganic building brick forming metal organic frameworks with exceptional stability.

              Porous crystals are strategic materials with industrial applications within petrochemistry, catalysis, gas storage, and selective separation. Their unique properties are based on the molecular-scale porous character. However, a principal limitation of zeolites and similar oxide-based materials is the relatively small size of the pores, typically in the range of medium-sized molecules, limiting their use in pharmaceutical and fine chemical applications. Metal organic frameworks (MOFs) provided a breakthrough in this respect. New MOFs appear at a high and an increasing pace, but the appearances of new, stable inorganic building bricks are rare. Here we present a new zirconium-based inorganic building brick that allows the synthesis of very high surface area MOFs with unprecedented stability. The high stability is based on the combination of strong Zr-O bonds and the ability of the inner Zr6-cluster to rearrange reversibly upon removal or addition of mu3-OH groups, without any changes in the connecting carboxylates. The weak thermal, chemical, and mechanical stability of most MOFs is probably the most important property that limits their use in large scale industrial applications. The Zr-MOFs presented in this work have the toughness needed for industrial applications; decomposition temperature above 500 degrees C and resistance to most chemicals, and they remain crystalline even after exposure to 10 tons/cm2 of external pressure.
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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                ANALAO
                The Analyst
                Analyst
                Royal Society of Chemistry (RSC)
                0003-2654
                1364-5528
                May 16 2023
                2023
                : 148
                : 10
                : 2200-2213
                Affiliations
                [1 ]National Engineering Research Center for Carbohydrate Synthesis, Key Lab of Fluorine and Silicon for Energy Materials and Chemistry of Ministry of Education, Key Laboratory for Green Chemistry of Jiangxi Province, Department of Chemistry and chemical engineering, Jiangxi Normal University, Nanchang 330022, People's Republic of China
                [2 ]Key Laboratory of Analysis and Detection for Food Safety (Ministry of Education of China and Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China
                Article
                10.1039/D3AN00222E
                37009770
                46f1904b-74ee-46b3-a85a-f51a6cd558ed
                © 2023

                http://rsc.li/journals-terms-of-use

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