Impact of Neoadjuvant Systemic Therapy on Pancreatic Fistula Rates Following Pancreatectomy: a Population-Based Propensity-Matched Analysis.

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Abstract

Postoperative pancreatic fistula (POPF) drives morbidity and mortality following pancreatectomy. Use of neoadjuvant chemotherapy (NAC) has recently increased in the treatment of potentially resectable pancreatic ductal adenocarcinoma (PDAC). This study examined the effect of NAC on POPF rates and postoperative outcomes in PDAC.

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Journal

Journal ID (iso-abbrev): J Gastrointest Surg

Title: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1873-4626

ISSN (Print): 1091-255X

Publication date (Electronic): March 2021

Volume: 25

Issue: 3

Affiliations

[1 ] Department of Surgical Oncology, Edward-Elmhurst Health, 120 Spalding Drive, Ste 205, Naperville, IL, 60540, USA. Fadi.Dahdaleh@EEHealth.org.

[2 ] Department of General Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL, USA.

[3 ] Department of Surgical Oncology, H. Lee Moffitt Cancer and Research Institute, Tampa, FL, USA.

[4 ] Department of Colon and Rectal Surgery, Surgical Oncology, City of Hope Medical Foundation, Upland, CA, USA.

[5 ] Department of Surgical Oncology, Edward-Elmhurst Health, 120 Spalding Drive, Ste 205, Naperville, IL, 60540, USA.

Article

Publisher Item ID: 10.1007/s11605-020-04581-y

DOI: 10.1007/s11605-020-04581-y

PubMed ID: 32253648

SO-VID: 462585b2-ab07-44ba-8c11-4b1e6b556dae

History

Keywords: Neoadjuvant therapy,Pancreatic ductal carcinoma,Pancreatic fistula

Data availability:

Keywords: Neoadjuvant therapy, Pancreatic ductal carcinoma, Pancreatic fistula

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