ERS International Congress 2023: highlights from the Respiratory Intensive Care Assembly

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Early career members of Assembly 2 (Respiratory Intensive Care) attended the 2023 European Respiratory Society International Congress in Milan, Italy. The conference covered acute and chronic respiratory failure. Sessions of interest to our assembly members and to those interested in respiratory critical care are summarised in this article and include the latest updates in respiratory intensive care, in particular acute respiratory distress syndrome and mechanical ventilation.

Shareable abstract

The latest updates in respiratory intensive care, in particular ARDS and mechanical ventilation, presented at #ERSCongress 2023 in Milan, are summarised by the early career members of @ERSAssembly2 (Respiratory Intensive Care) https://bit.ly/3GvBzFy

Related collections

Most cited references 115

Record: found
Abstract: found
Article: not found

Acute respiratory distress syndrome: the Berlin Definition.

V Ranieri, Gordon D Rubenfeld, B Taylor Thompson … (2013)

The acute respiratory distress syndrome (ARDS) was defined in 1994 by the American-European Consensus Conference (AECC); since then, issues regarding the reliability and validity of this definition have emerged. Using a consensus process, a panel of experts convened in 2011 (an initiative of the European Society of Intensive Care Medicine endorsed by the American Thoracic Society and the Society of Critical Care Medicine) developed the Berlin Definition, focusing on feasibility, reliability, validity, and objective evaluation of its performance. A draft definition proposed 3 mutually exclusive categories of ARDS based on degree of hypoxemia: mild (200 mm Hg < PaO2/FIO2 ≤ 300 mm Hg), moderate (100 mm Hg < PaO2/FIO2 ≤ 200 mm Hg), and severe (PaO2/FIO2 ≤ 100 mm Hg) and 4 ancillary variables for severe ARDS: radiographic severity, respiratory system compliance (≤40 mL/cm H2O), positive end-expiratory pressure (≥10 cm H2O), and corrected expired volume per minute (≥10 L/min). The draft Berlin Definition was empirically evaluated using patient-level meta-analysis of 4188 patients with ARDS from 4 multicenter clinical data sets and 269 patients with ARDS from 3 single-center data sets containing physiologic information. The 4 ancillary variables did not contribute to the predictive validity of severe ARDS for mortality and were removed from the definition. Using the Berlin Definition, stages of mild, moderate, and severe ARDS were associated with increased mortality (27%; 95% CI, 24%-30%; 32%; 95% CI, 29%-34%; and 45%; 95% CI, 42%-48%, respectively; P < .001) and increased median duration of mechanical ventilation in survivors (5 days; interquartile [IQR], 2-11; 7 days; IQR, 4-14; and 9 days; IQR, 5-17, respectively; P < .001). Compared with the AECC definition, the final Berlin Definition had better predictive validity for mortality, with an area under the receiver operating curve of 0.577 (95% CI, 0.561-0.593) vs 0.536 (95% CI, 0.520-0.553; P < .001). This updated and revised Berlin Definition for ARDS addresses a number of the limitations of the AECC definition. The approach of combining consensus discussions with empirical evaluation may serve as a model to create more accurate, evidence-based, critical illness syndrome definitions and to better inform clinical care, research, and health services planning.

0 comments Cited 2507 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome

Lila Bouadma, Alain Combes, David Hajage … (2018)

The efficacy of venovenous extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory distress syndrome (ARDS) remains controversial.

0 comments Cited 617 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials.

Carolyn S Calfee, Kevin Delucchi, Polly Parsons … (2014)

Subphenotypes have been identified within heterogeneous diseases such as asthma and breast cancer, with important therapeutic implications. We assessed whether subphenotypes exist within acute respiratory distress syndrome (ARDS), another heterogeneous disorder.

0 comments Cited 419 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Journal

Journal ID (nlm-ta): ERJ Open Res

Journal ID (iso-abbrev): ERJ Open Res

Journal ID (publisher-id): ERJOR

Journal ID (hwp): erjor

Title: ERJ Open Research

Publisher: European Respiratory Society

ISSN (Electronic): 2312-0541

Publication date Collection: March 2024

Publication date (Electronic): 22 April 2024

Volume: 10

Issue: 2

Electronic Location Identifier: 00886-2023

Affiliations

[1 ]Sorbonne Université, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France

[2 ]Academic unit of the University Institute of Health Science H.A. Barceló Foundation, La Rioja, Argentina

[3 ]APHP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, Site Pitié-Salpêtrière, Service de Pneumologie, Paris, France

[4 ]Pulmonology Department, General University Hospital of Castellón, Castellón, Spain

[5 ]Translational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain

[6 ]CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain

[7 ]St Vincent's Health Network Sydney, Sydney, Australia

[8 ]University of Sydney, Sydney, Australia

[9 ]Assistance Publique Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Centre de Référence de l'Hypertension Pulmonaire, Hôpital Bicêtre, Le Kremlin Bicêtre, France

[10 ]Université Paris–Saclay, Faculté de Médecine, Le Kremlin Bicêtre, France

[11 ]University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

[12 ]Institute Germans Trias i Pujol, Badalona, Spain

[13 ]Department of Pulmonology, University Hospital Dubrava, Zagreb, Croatia

[14 ]Respiratory Research Group, Hull York Medical School, Hull, UK

[15 ]Department of Medicine, Letterkenny University Hospital, Donegal, Ireland

[16 ]Department of Respiratory Medicine, King's College Hospital NHS Foundation Trust, London, UK

[17 ]Departamento de Pneumonologia, Centro Hospitalar de Vila Nova de Gaia/Espinho, Oporto, Portugal

[18 ]Pulmonology Department, Hospital de Braga, Braga, Portugal

[19 ]1st Respiratory Department, Medical School, National and Kapodistrian University of Athens, “Sotiria” Chest Hospital, Athens, Greece

[20 ]Department of Pneumology and Critical Care Medicine, ARDS and ECMO Centre, Cologne-Merheim Hospital, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, Cologne, Germany

[21 ]Department of Internal Medicine II, University Medical Centre Regensburg, Regensburg, Germany

Author notes

Corresponding author: Christoph Fisser ( christoph.fisser@ 123456ukr.de )

Author information

Clara Bianquis https://orcid.org/0000-0002-6480-6981

Sebastian Leiva Agüero https://orcid.org/0000-0002-4702-294X

Alejandro Golfe Bonmatí https://orcid.org/0000-0001-5946-7092

Thomas Lacoste-Palasset https://orcid.org/0000-0003-3543-6675

Dominic L. Sykes https://orcid.org/0000-0002-0925-7772

Cristiano van Zeller https://orcid.org/0000-0001-8289-0550

Pedro Viegas https://orcid.org/0000-0001-8972-415X

Article

Publisher ID: 00886-2023

DOI: 10.1183/23120541.00886-2023

PMC ID: 11033729

PubMed ID: 38651090

SO-VID: 458d939e-4b97-406c-a915-80ffca650e70

License:

This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ 123456ersnet.org

History

Date received : 23 November 2023

Date accepted : 28 November 2023

Comments

Comment on this article

scite_

Cited by 1

ERS International Congress 2023: highlights from the Respiratory Clinical Care and Physiology Assembly
Authors: Apolline Gonsard, Evgeni Mekov, Sarah Barron …

See all cited by

Most referenced authors 4,007

See all reference authors

ERS International Congress 2023: highlights from the Respiratory Intensive Care Assembly

Read this article at

Abstract

Shareable abstract

Related collections

European Respiratory Society: COVID-19

Most cited references 115

Acute respiratory distress syndrome: the Berlin Definition.

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome

Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials.

Author and article information

Journal

Affiliations

Author notes

Author information

Article

History

Categories

Comments

Comment on this article

Similar content 196

Cited by 1

Most referenced authors 4,007