The cancer genome.

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Abstract

All cancers arise as a result of changes that have occurred in the DNA sequence of the genomes of cancer cells. Over the past quarter of a century much has been learnt about these mutations and the abnormal genes that operate in human cancers. We are now, however, moving into an era in which it will be possible to obtain the complete DNA sequence of large numbers of cancer genomes. These studies will provide us with a detailed and comprehensive perspective on how individual cancers have developed.

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Journal

Journal ID (iso-abbrev): Nature

Title: Nature

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1476-4687

ISSN (Print): 0028-0836

Publication date (Electronic): Apr 09 2009

Volume: 458

Issue: 7239

Affiliations

[1 ] Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. mrs@sanger.ac.uk

Article

Publisher Item ID: nature07943 Mid ID: UKMS27394

DOI: 10.1038/nature07943

PMC ID: 2821689

PubMed ID: 19360079

SO-VID: 44a428ab-a1fc-4d39-98a2-3e4b6d188cea

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