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      Hypoxic effects on the mitochondrial content and functions of the placenta in fetal growth restriction.

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          Abstract

          In this study we examined the hypothesis that a hypoxic intrauterine environment causes mitochondrial dysfunction of trophoblasts in fetal growth restriction (FGR).

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          Author and article information

          Journal
          Placenta
          Placenta
          Elsevier BV
          1532-3102
          0143-4004
          Oct 2021
          : 114
          Affiliations
          [1 ] Departments of Pathology, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
          [2 ] Biobank, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
          [3 ] Division of Maternal-Fetal Medicine and Perinatal Research, Department of Obstetrics and Gynecology, The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
          [4 ] Departments of Pathology, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. Electronic address: zhanghj815@sjtu.edu.cn.
          Article
          S0143-4004(21)00582-8
          10.1016/j.placenta.2021.09.003
          34509037
          43ebe98f-e90a-4e8e-926b-8c5ec6ce00ae
          History

          Mitophagy,Placental dysfunction,FGR,Hypoxia,Mitochondria
          Mitophagy, Placental dysfunction, FGR, Hypoxia, Mitochondria

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