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Cytogenetic Investigation in 136 Consecutive Stillbirths: Does the Tissue Type Affect the Success Rate of Chromosomal Microarray Analysis and Karyotype?
Borja Marquès
1 ,
Leticia Benitez
1 ,
Anna Peguero
1 ,
Irene Madrigal
2 ,
Olga Gómez
1 ,
Francesc Figueras
1 ,
Antoni Borrell
3
2020
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Abstract
Chromosomal anomalies are a recognized cause of stillbirth, accounting for 6-17% of the cases. As a diagnostic laboratory method in this setting, conventional karyotyping has two main drawbacks: the need for viable fetal cells in a dead fetus and its limited resolution as compared to alternative techniques.