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      Domiciliary High-Flow Nasal Cannula Oxygen Therapy for Patients with Stable Hypercapnic Chronic Obstructive Pulmonary Disease. A Multicenter Randomized Crossover Trial

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          Abstract

          A growing evidence base suggests a benefit of using high-flow nasal cannula oxygen therapy in the acute setting. However, the clinical benefit of domiciliary use of high-flow nasal cannula oxygen therapy in patients with chronic hypercapnic respiratory failure due to chronic obstructive pulmonary disease remains unclear.

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          Physiologic Effects of High-Flow Nasal Cannula in Acute Hypoxemic Respiratory Failure.

          Tommaso Mauri, Cecilia Turrini, Nilde Eronia … (2017)
          High-flow nasal cannula (HFNC) improves the clinical outcomes of nonintubated patients with acute hypoxemic respiratory failure (AHRF).
          Article 0 comments Cited 211 times – based on 0 reviews     Review now
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            Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation : A Randomized Clinical Trial

            Patrick B. Murphy, Sunita Rehal, Gill Arbane … (2017)
            Outcomes after exacerbations of chronic obstructive pulmonary disease (COPD) requiring acute noninvasive ventilation (NIV) are poor and there are few treatments to prevent hospital readmission and death.
            Article 0 comments Cited 188 times – based on 0 reviews     Review now
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              The use of uniaxial accelerometry for the assessment of physical-activity-related energy expenditure: a validation study against whole-body indirect calorimetry.

              Yves Schutz, Munehiro Shindo, Hiroaki Tanaka … (2004)
              Assessing the total energy expenditure (TEE) and the levels of physical activity in free-living conditions with non-invasive techniques remains a challenge. The purpose of the present study was to investigate the accuracy of a new uniaxial accelerometer for assessing TEE and physical-activity-related energy expenditure (PAEE) over a 24 h period in a respiratory chamber, and to establish activity levels based on the accelerometry ranges corresponding to the operationally defined metabolic equivalent (MET) categories. In study 1, measurement of the 24 h energy expenditure of seventy-nine Japanese subjects (40 (SD 12) years old) was performed in a large respiratory chamber. During the measurements, the subjects wore a uniaxial accelerometer (Lifecorder; Suzuken Co. Ltd, Nagoya, Japan) on their belt. Two moderate walking exercises of 30 min each were performed on a horizontal treadmill. In study 2, ten male subjects walked at six different speeds and ran at three different speeds on a treadmill for 4 min, with the same accelerometer. O2 consumption was measured during the last minute of each stage and was expressed in MET. The measured TEE was 8447 (SD 1337) kJ/d. The accelerometer significantly underestimated TEE and PAEE (91.9 (SD 5.4) and 92.7 (SD 17.8) % chamber value respectively); however, there was a significant correlation between the two values (r 0.928 and 0.564 respectively; P<0.001). There was a strong correlation between the activity levels and the measured MET while walking (r(2) 0.93; P<0.001). Although TEE and PAEE were systematically underestimated during the 24 h period, the accelerometer assessed energy expenditure well during both the exercise period and the non-structured activities. Individual calibration factors may help to improve the accuracy of TEE estimation, but the average calibration factor for the group is probably sufficient for epidemiological research. This method is also important for assessing the diurnal profile of physical activity.
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                Author and article information

                Journal
                Title: Annals of the American Thoracic Society
                Abbreviated Title: Annals ATS
                Publisher: American Thoracic Society
                ISSN (Print): 2329-6933
                ISSN (Electronic): 2325-6621
                Publication date Created: April 2018
                Publication date (Print): April 2018
                Volume: 15
                Issue: 4
                Pages: 432-439
                Affiliations
                [1 ]Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan
                [2 ]Department of Medical Statistics, Translational Research Informatics Center, Kobe, Japan
                [3 ]Department of Respiratory Medicine, Maebashi Red Cross Hospital, Maebashi, Japan
                [4 ]Department of Respiratory Medicine, Ogaki Municipal Hospital, Gifu, Japan
                [5 ]Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan
                [6 ]Department of Pulmonary Medicine, National Hospital Organization Matsue Medical Center, Matsue, Japan
                [7 ]Department of Respiratory Medicine, Kurashiki Central Hospital, Kurashiki, Japan
                [8 ]Department of Respiratory Medicine, St. Luke’s International Hospital, Tokyo, Japan
                [9 ]Department of Respiratory Medicine, National Hospital Organization Ehime Medical Center, Ehime, Japan; and
                [10 ]Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
                Article
                DOI: 10.1513/AnnalsATS.201706-425OC
                PubMed ID: 29283682
                SO-VID: 4253165d-836a-41d3-837f-47d79db362be
                Copyright © © 2018
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