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      Intact blood-brain barrier during spontaneous attacks of migraine without aura: a 3T DCE-MRI study.

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          Abstract

          The integrity of the blood-brain barrier (BBB) has been questioned in migraine, but BBB permeability has never been investigated during spontaneous migraine attacks. In the present study, BBB permeability during spontaneous attacks of migraine without aura was investigated compared to an interictal state.

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          Author and article information

          Journal
          Eur. J. Neurol.
          European journal of neurology
          Wiley
          1468-1331
          1351-5101
          September 2017
          : 24
          : 9
          Affiliations
          [1 ] Department of Neurology, Faculty of Health and Medical Sciences, Danish Headache Center, Rigshospitalet Glostrup, University of Copenhagen, Copenhagen, Denmark.
          [2 ] Functional Imaging Unit, Department of Clinical Physiology, Nuclear Medicine and PET, Faculty of Health and Medical Sciences, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
          [3 ] Department of Radiology, Faculty of Health and Medical Sciences, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
          [4 ] Faculty of Health and Medical Science, Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
          Article
          10.1111/ene.13341
          28727225
          41f6b020-359e-422c-9364-a24a38386aa9
          History

          blood−brain barrier disruption in migraine,migraine mechanisms,neuroimaging of migraine,migraine pathophysiology

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