A case of aleukemic leukemia cutis after COVID-19 infection presenting as facial rash. – ScienceOpen
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      A case of aleukemic leukemia cutis after COVID-19 infection presenting as facial rash.

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          Abstract

          Aleukemic leukemia cutis (ALC) is a rare condition that is characterized by leukemic cells in the skin before presenting in the peripheral blood or bone marrow. We report a case of a 43-year-old woman who underwent assessment for bilateral facial nodules arising 1 month after COVID-19 infection. A punch biopsy specimen showed a malignant neoplasm primarily composed of immature blasts dissecting through the collagen in the dermis, concerning for myeloid sarcoma versus leukemia cutis. Bone marrow and blood specimens were negative for hematologic malignancy. The patient was appropriately treated with chemotherapy and is recovering well. This report highlights an interesting case of ALC following COVID-19 infection presenting as an isolated facial rash. Whether there is a true relationship between the patient's COVID-19 infection and her abrupt presentation of leukemia remains unclear, but we present this case regardless, in an effort to highlight a potentially unique association requiring further study.

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          Author and article information

          Journal
          J Cutan Pathol
          Journal of cutaneous pathology
          Wiley
          1600-0560
          0303-6987
          Jul 2023
          : 50
          : 7
          Affiliations
          [1 ] University of Virginia, Charlottesville, Virginia, USA.
          [2 ] Laboratório Bacchi, Botucatu, Brazil.
          [3 ] Department of Pathology, University of Virginia, Charlottesville, Virginia, USA.
          [4 ] Department of Dermatology, University of Virginia, Charlottesville, Virginia, USA.
          Article
          10.1111/cup.14431
          37069795
          4165ed13-9a39-46b4-9cd5-ac1be38f13ff
          History

          COVID-19 infection,acute myeloid leukemia,facial rash,aleukemic leukemia cutis

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