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      Relationships among self-esteem, ego-resilience, and caregiver burden among families of children with hematologic and oncologic disease: A cross-sectional study

      research-article
      a , b ,
      Heliyon
      Elsevier
      Caregiver burden, Ego-resilience, Self-esteem, Childhood cancer

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          Abstract

          Background

          Pediatric hematology and oncology disease is a physically and emotionally demanding health condition for families. High self-esteem and ego-resilience among caregivers, which have recently gained increased recognition, might help ease caregiver burdens. Few studies, however, have simultaneously investigated the relationships between self-esteem, ego-resilience, and caregiver burden among caregivers of children with hematologic and oncologic disease.

          Objective

          The purpose of this study is to investigate the relationships between caregiver burden, self-esteem, and ego-resilience and examine whether ego-resilience plays a role in mediating the relationship between self-esteem and caregiver burden among family caregivers of children with hematologic and oncologic disease.

          Design

          Descriptive correlational study.

          Setting

          The outpatient clinic of the department of pediatric hematology and oncology at a flagship university hospital in a metropolitan city in South Korea.

          Participants

          The sample comprised 109 primary family caregivers of children with hematologic and oncologic disease. Convenience sampling method was used.

          Methods

          The participants completed the Ego-Resiliency Scale, Rosenberg Self-Esteem Scale, and Family Burden Questionnaire. One-way analysis of variance, independent t-tests, and correlation analyses were conducted using IBM SPSS 25.0. The mediating effect of ego-resilience was estimated using the PROCESS macro and bootstrap method in SPSS.

          Results

          Caregiver burden showed significant negative associations with self-esteem and ego-resilience, with moderate effect sizes (r = −.391 and −0.361, respectively, p = .001). Ego-resilience mediated the relationship between self-esteem and caregiver burden (b = −0.019; 95 % bias-corrected bootstrap confidence interval −0.035 and −0.001).

          Conclusions

          Self-esteem and ego-resilience may lessen caregiver burden among families of children with hematologic and oncologic disease, and self-esteem of caregivers tends to promote their ego-resilience. Therefore, self-esteem and ego-resilience should be improved among family caregivers to reduce their caregiver burden.

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          Most cited references37

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          The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.

          In this article, we attempt to distinguish between the properties of moderator and mediator variables at a number of levels. First, we seek to make theorists and researchers aware of the importance of not using the terms moderator and mediator interchangeably by carefully elaborating, both conceptually and strategically, the many ways in which moderators and mediators differ. We then go beyond this largely pedagogical function and delineate the conceptual and strategic implications of making use of such distinctions with regard to a wide range of phenomena, including control and stress, attitudes, and personality traits. We also provide a specific compendium of analytic procedures appropriate for making the most effective use of the moderator and mediator distinction, both separately and in terms of a broader causal system that includes both moderators and mediators.
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            • Article: not found

            Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

            In a phase 1 trial, axicabtagene ciloleucel (axi-cel), an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, showed efficacy in patients with refractory large B-cell lymphoma after the failure of conventional therapy.
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              Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

              In a single-center phase 1-2a study, the anti-CD19 chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL).
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                Author and article information

                Contributors
                Journal
                Heliyon
                Heliyon
                Heliyon
                Elsevier
                2405-8440
                18 November 2023
                December 2023
                18 November 2023
                : 9
                : 12
                : e22652
                Affiliations
                [a ]Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, South Korea
                [b ]College of Nursing, Kyungpook National University, Daegu, South Korea
                Author notes
                []Corresponding author. College of Nursing, Kyungpook National University, South Korea. bukpark@ 123456knu.ac.kr
                Article
                S2405-8440(23)09860-2 e22652
                10.1016/j.heliyon.2023.e22652
                10711119
                38089992
                412fe52e-5ba4-425f-8c74-604e4bb33c53
                © 2023 The Authors. Published by Elsevier Ltd.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 30 April 2023
                : 15 November 2023
                : 16 November 2023
                Categories
                Research Article

                caregiver burden,ego-resilience,self-esteem,childhood cancer

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