Current understanding of human megakaryocytic-erythroid progenitors and their fate determinants.

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Abstract

This review focuses on our current understanding of fate decisions in bipotent megakaryocyte-erythroid progenitors (MEPs). Although extensive research has been carried out over decades, our understanding of how MEP commit to the erythroid versus megakaryocyte fate remains unclear.

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Journal

Journal ID (iso-abbrev): Curr Opin Hematol

Title: Current opinion in hematology

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1531-7048

ISSN (Print): 1065-6251

Publication date (Electronic): Jan 2021

Volume: 28

Issue: 1

Affiliations

[1 ] Department of Cell Biology.

[2 ] Yale Stem Cell Center.

[3 ] Department of Pathology.

[4 ] Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Article

Mid ID: NIHMS1651635 Publisher Item ID: 00062752-202101000-00005

DOI: 10.1097/MOH.0000000000000625

PMC ID: 7737300

PubMed ID: 33186151

SO-VID: 408c9cb4-bb55-4243-927b-80d18bfacbc7

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