Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial.

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Abstract

In the Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) improved outcome compared with angiography-guided PCI for up to 2 years of follow-up. The aim in this study was to investigate whether the favourable clinical outcome with the FFR-guided PCI in the FAME study persisted over a 5-year follow-up.

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Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): Nov 7 2015

Volume: 386

Issue: 10006

Affiliations

[1 ] Department of Cardiology, Catharina Hospital Eindhoven, Eindhoven, Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.

[2 ] Cardiovascular Center Aalst, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.

[3 ] Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

[4 ] Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

[5 ] Medizinische Poliklinik, Campus-Innenstadt, University Hospital, Munich, Germany.

[6 ] King's College Hospital, London, UK.

[7 ] Heart Centre, Royal Victoria Hospital, Belfast, UK.

[8 ] Golden Jubilee National Hospital, Glasgow, UK.

[9 ] Northeast Cardiology Associates and Eastern Maine Medical Center, Bangor, ME, USA.

[10 ] Stanford University Medical Center and Palo Alto VA Health Care Systems, Stanford, CA, USA.

[11 ] Cardiovascular Center Aalst, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium.

[12 ] Department of Cardiology, Catharina Hospital Eindhoven, Eindhoven, Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands. Electronic address: nico.pijls@inter.nl.net.

Article

Publisher Item ID: S0140-6736(15)00057-4

DOI: 10.1016/S0140-6736(15)00057-4

PubMed ID: 26333474

SO-VID: 4057283f-ffd0-4890-8218-755404bf51bc

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