The outbreak of COVID-19 has accelerated the building of resilient supply chains, and supply chain digitalization is gradually being recognized as an enabling means to this end. Nevertheless, scholars generally agree that more empirical studies will need to be conducted on how digitalization can facilitate supply chain resilience at various stages and enhance supply chain performance in a highly uncertain environment. To echo the call, this study develops a theoretical influence mechanism of “supply chain digitalization → supply chain resilience → supply chain performance” based on dynamic capability theory. The proposed relationships are validated using survey data collected from 210 Chinese manufacturing companies. The results help identify the paths digitalization and supply chain resilience can take to improve supply chain performance in a turbulent environment. The different roles of three supply chain resilience capabilities, namely absorptive capability (before the disruption), response capability (during the disruption), and recovery capability (after the disruption), which impact on supply chain performance differently, are highlighted. In addition, it is found that digitalization can bring a differential impact on these three supply chain resilience capabilities through different aspects of resource and structural adjustment measures. The findings also confirm the mediating role of absorptive capability, response capability, and recovery capability between digitalization and supply chain performance. During crisis, supply chain digitalization can increase cost-effectiveness, enhance information and communication efficiency, and promote supply chain resilience to achieve better performance. For theoretical contribution, this study enriches the research on supply chain digitalization and resilience by underpinning the relationships between the two with dynamic capability theory. For practical contribution, the research findings provide insights for enterprises to leverage digitalization to strengthen resilience in supply chain.