3
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Association between cardiovascular health and all-cause mortality risk in patients with osteoarthritis

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Background

          This study was to explore the relationship between cardiovascular health (CVH) and the risk of all-cause mortality in patients with osteoarthritis (OA).

          Methods

          This cohort study retrieved the data of 3642 patients with OA aged ≥ 20 years from the 2007—2018 National Health and Nutrition Examination Survey (NHANES). CVH was evaluated based on Life’s Essential 8 (LE8) includes diet, physical activity, nicotine exposure, sleep health, body mass index, blood lipids, blood glucose, and blood pressure. The outcome of all-cause mortality was assessed using the death certificate records of participants from the National Death Index. Variables that might affect all-cause mortality were used as covariates. The weighted univariate COX proportional hazards model was used to explore the association between each covariate and all-cause mortality. The weighted univariate and multivariate COX proportional hazards models were used to explore the association between different CVH levels and all-cause mortality. A restricted cubic spline (RCS) curve was plotted to show the association between different CVH levels and all-cause mortality in OA patients. Hazard ratio (HR) and 95% confidence interval (CI) were calculated.

          Results

          Findings show that people with moderate CVH (HR = 0.67, 95% CI = 0.45—0.98) and high CVH (HR = 0.47, 95% CI = 0.26—0.87) were associated with reduced risk of all-cause mortality in patients with OA. The HR of all-cause mortality in patients with OA decreased by 0.12 as per 10 points increase of LE8 score (HR = 0.81, 95% CI = 0.73—0.90). The RCS curve revealed that the HR of all-cause mortality decreased with the increase in LE8 score. The survival probability of patients in the high CVH group was higher than the moderate CVH group and low CVH group ( p = 0.002).

          Conclusion

          Moderate-to-high CVH is associated with a decreased risk of all-cause mortality in patients with OA. These findings might provide a reference for the formulation of prognosis improvement strategies for the management of patients with OA.

          Supplementary Information

          The online version contains supplementary material available at 10.1186/s12891-024-07729-y.

          Related collections

          Most cited references42

          • Record: found
          • Abstract: found
          • Article: not found

          Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association

          In 2010, the American Heart Association defined a novel construct of cardiovascular health to promote a paradigm shift from a focus solely on disease treatment to one inclusive of positive health promotion and preservation across the life course in populations and individuals. Extensive subsequent evidence has provided insights into strengths and limitations of the original approach to defining and quantifying cardiovascular health. In response, the American Heart Association convened a writing group to recommend enhancements and updates. The definition and quantification of each of the original metrics (Life’s Simple 7) were evaluated for responsiveness to interindividual variation and intraindividual change. New metrics were considered, and the age spectrum was expanded to include the entire life course. The foundational contexts of social determinants of health and psychological health were addressed as crucial factors in optimizing and preserving cardiovascular health. This presidential advisory introduces an enhanced approach to assessing cardiovascular health: Life’s Essential 8. The components of Life’s Essential 8 include diet (updated), physical activity, nicotine exposure (updated), sleep health (new), body mass index, blood lipids (updated), blood glucose (updated), and blood pressure. Each metric has a new scoring algorithm ranging from 0 to 100 points, allowing generation of a new composite cardiovascular health score (the unweighted average of all components) that also varies from 0 to 100 points. Methods for implementing cardiovascular health assessment and longitudinal monitoring are discussed, as are potential data sources and tools to promote widespread adoption in policy, public health, clinical, institutional, and community settings.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Global, regional and national burden of osteoarthritis 1990-2017: a systematic analysis of the Global Burden of Disease Study 2017

            To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and Socio-demographic index (SDI; a composite of sociodemographic factors). Publicly available modelled data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 were used. The burden of OA was estimated for 195 countries and territories from 1990 to 2017, through a systematic analysis of prevalence and incidence modelled data using the methods reported in the GBD 2017 Study. All estimates were presented as counts and age-standardised rates per 100 000 population, with uncertainty intervals (UIs). Globally, the age-standardised point prevalence and annual incidence rate of OA in 2017 were 3754.2 (95% UI 3389.4 to 4187.6) and 181.2 (95% UI 162.6 to 202.4) per 100 000, an increase of 9.3% (95% UI 8% to 10.7%) and 8.2% (95% UI 7.1% to 9.4%) from 1990, respectively. In addition, global age-standardised YLD rate in 2017 was 118.8 (95% UI 59.5 to 236.2), an increase of 9.6% (95% UI 8.3% to 11.1%) from 1990. The global prevalence was higher in women and increased with age, peaking at the >95 age group among women and men in 2017. Generally, a positive association was found between the age-standardised YLD rate and SDI at the regional and national levels. Age-standardised prevalence of OA in 2017 ranged from 2090.3 to 6128.1 cases per 100 000 population. United States (6128.1 (95% UI 5729.3 to 6582.9)), American Samoa (5281 (95% UI 4688 to 5965.9)) and Kuwait (5234.6 (95% UI 4643.2 to 5953.6)) had the three highest levels of age-standardised prevalence. Oman (29.6% (95% UI 24.8% to 34.9%)), Equatorial Guinea (28.6% (95% UI 24.4% to 33.7%)) and the United States 23.2% (95% UI 16.4% to 30.5%)) showed the highest increase in the age-standardised prevalence during 1990–2017. OA is a major public health challenge. While there is remarkable international variation in the prevalence, incidence and YLDs due to OA, the burden is increasing in most countries. It is expected to continue with increased life expectancy and ageing of the global population. Improving population and policy maker awareness of risk factors, including overweight and injury, and the importance and benefits of management of OA, together with providing health services for an increasing number of people living with OA, are recommended for management of the future burden of this condition.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Tobacco Product Use Among Adults — United States, 2019

              Cigarette smoking remains the leading cause of preventable disease and death in the United States ( 1 ). The prevalence of current cigarette smoking among U.S. adults has declined over the past several decades, with a prevalence of 13.7% in 2018 ( 2 ). However, a variety of combustible, noncombustible, and electronic tobacco products are available in the United States ( 1 , 3 ). To assess recent national estimates of tobacco product use among U.S. adults aged ≥18 years, CDC analyzed data from the 2019 National Health Interview Survey (NHIS). In 2019, an estimated 50.6 million U.S. adults (20.8%) reported currently using any tobacco product, including cigarettes (14.0%), e-cigarettes (4.5%), cigars (3.6%), smokeless tobacco (2.4%), and pipes* (1.0%). † Most current tobacco product users (80.5%) reported using combustible products (cigarettes, cigars, or pipes), and 18.6% reported using two or more tobacco products. § The prevalence of any current tobacco product use was higher among males; adults aged ≤65 years; non-Hispanic American Indian/Alaska Native (AI/AN) adults; those whose highest level of educational attainment was a General Educational Development (GED) certificate; those with an annual household income 30% or unweighted denominator 30% or unweighted denominator <50. The figure is a bar chart showing the cigarette smoking status (current, former, or never) among current adult e-cigarette users, by age group. The prevalence of any current tobacco product use was higher among males (26.2%) than among females (15.7%) and among those aged 25–44 years (25.3%), 45–64 years (23.0%), or 18–24 years (18.2%) than among those aged ≥65 years (11.4%) (Table). Current tobacco product use was also higher among non-Hispanic AI/AN adults (29.3%), non-Hispanic adults of other †††† races (28.1%), non-Hispanic White adults (23.3%), non-Hispanic Black adults (20.7%), and Hispanic or Latino adults (13.2%) than among non-Hispanic Asian adults (11.0%); and among those living in the Midwest (23.7%) or South (22.9%) than among those in the Northeast (18.5%) or West (16.4%). The prevalence of current tobacco product use was higher among those whose highest educational attainment was a GED (43.7%) than among those with other levels of education; among those who were divorced/separated/widowed (23.5%) or single/never married/not living with a partner (23.0%) than among those married/living with a partner (19.2%); among those who had annual household income of <$35,000 (27.0%) than among those with higher income; and among LGB adults (29.9%) than among those who were heterosexual/straight (20.5%). Prevalence was also higher among adults who were uninsured (30.2%), insured by Medicaid (30.0%), or had some other public insurance (25.6%) than among those with private insurance (18.0%) or Medicare only (11.4%); among those who had a disability (26.9%) compared with those without (20.1%); and among those who had GAD-7 scores indicating mild (30.4%), moderate (34.2%) or severe (45.3%) anxiety than among those indicating no or minimal (18.4%) anxiety. Discussion In 2019, approximately one in five U.S. adults (50.6 million) reported currently using any tobacco product. Cigarettes were the most commonly used tobacco product among adults, and combustible tobacco products (cigarettes, cigars, or pipes) were used by most (80.5%) adult tobacco product users. Most of the death and disease from tobacco use in the United States is primarily caused by cigarettes and other combustible products ( 1 ); therefore, continued efforts to reduce all forms of combustible tobacco smoking among U.S. adults are warranted. Moreover, approximately one in five current tobacco product users (18.6%) reported using two or more tobacco products, and differences in prevalence of tobacco use were also seen across population groups, with higher prevalence among those with a GED, American Indian/Alaska Natives, uninsured adults and adults with Medicaid, and LGB adults. Each of these groups has experienced social, economic, and environmental stressors that might contribute to higher tobacco use prevalence ( 6 ). Comprehensive strategies at the national, state, and local levels, including targeted interventions and tailored community engagement, can reduce tobacco-related disease and death and help to mitigate tobacco-related disparities ( 1 , 4 , 6 ). U.S. adults also reported using various noncigarette tobacco products, with e-cigarettes being the most commonly used noncigarette tobacco product (4.5%). E-cigarette use was highest among adults aged 18–24 years (9.3%), with over half (56.0%) of these young adults reporting that they had never smoked cigarettes. In addition, the tobacco product with the highest percentage of users aged 18–24 years (24.5%) was e-cigarettes. E-cigarettes contain nicotine, which is highly addictive, can prime the brain for addiction to other drugs, and can harm brain development, which continues until about age 25 years ( 3 ). Although e-cigarette use was lower among the older age groups, more than 40% of e-cigarette users in the 25–44, 45–64 and ≥65 years age groups reported being former smokers. Although some evidence suggests that the use of e-cigarettes containing nicotine and more frequent use of e-cigarettes are associated with increased smoking cessation, smokers need to completely stop smoking cigarettes and stop using any other tobacco product to achieve meaningful health benefits ( 6 , 7 ). The U.S. Surgeon General concluded that there is presently inadequate evidence to conclude that e-cigarettes, in general, increase smoking cessation, and further research is needed on the effects that e-cigarettes have on cessation ( 7 ). Therefore, continued efforts to reduce use of all tobacco products, combustible and noncombustible, are needed. The findings in this report are subject to at least four limitations. First, the 59.1% response rate might have resulted in nonresponse bias, although sample weighting is designed to account for this. Second, self-reported responses were not validated by biochemical testing for cotinine (a biomarker indicating nicotine exposure); however, there is high correlation between self-reported smoking and smokeless use and cotinine levels ( 8 , 9 ). Third, because NHIS is limited to the noninstitutionalized U.S. civilian population, these results might not be generalizable to institutionalized populations and persons in the military. Finally, this analysis does not provide comparisons of prevalence estimates with previous surveys because changes in weighting and design methodology for the 2019 NHIS have the potential to affect comparisons of weighted survey estimates over time. §§§§ The implementation of comprehensive, evidence-based, population-level interventions in coordination with regulation of tobacco products, can reduce tobacco-related disease, disparities, and death in the United States ( 1 , 4 ). These evidence-based, population-level strategies include implementation of tobacco price increases, comprehensive smoke-free policies, high-impact antitobacco media campaigns, and barrier-free cessation coverage ( 1 ). As part of a comprehensive approach, targeted interventions are also warranted to reach subpopulations with the highest prevalence of use, which might vary by tobacco product type. Summary What is already known about this topic? Cigarette smoking remains the leading cause of preventable disease and death in the United States; however, a variety of new combustible, noncombustible, and electronic tobacco products are available in the United States. What is added by this report? In 2019, approximately 20.8% of U.S. adults (50.6 million) currently used any tobacco product. Cigarettes were the most commonly used tobacco product among adults, and e-cigarettes were the most commonly used noncigarette tobacco product (4.5%). The highest prevalence of e-cigarette use was among smokers aged 18–24 years (9.3%), with over half (56.0%) of these young adults reporting that they had never smoked cigarettes. What are the implications for public health practice? The implementation of comprehensive, evidence-based, population-level interventions, combined with targeted strategies, in coordination with regulation of tobacco products, can reduce tobacco-related disease and death in the United States. As part of a comprehensive approach, targeted interventions are also warranted to reach subpopulations with the greatest use, which might vary by tobacco product type.
                Bookmark

                Author and article information

                Contributors
                fanghuo004@outlook.com
                Journal
                BMC Musculoskelet Disord
                BMC Musculoskelet Disord
                BMC Musculoskeletal Disorders
                BioMed Central (London )
                1471-2474
                14 August 2024
                14 August 2024
                2024
                : 25
                : 641
                Affiliations
                [1 ]Department of Bone and Joint Surgery, Binzhou Medical University Hospital, ( https://ror.org/008w1vb37) No. 661 Huanghe 2nd Road, Binzhou, Shandong Province 256600 China
                [2 ]The Department of Nephrology, Binzhou Medical University Hospital, ( https://ror.org/008w1vb37) Binzhou, Shandong Province 256600 China
                Article
                7729
                10.1186/s12891-024-07729-y
                11323624
                39143482
                3eda9f87-c3ee-46cd-8cfa-bc94c15c020a
                © The Author(s) 2024

                Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

                History
                : 24 January 2024
                : 23 July 2024
                Categories
                Research
                Custom metadata
                © BioMed Central Ltd., part of Springer Nature 2024

                Orthopedics
                cardiovascular health,mortality,osteoarthritis,le8 score
                Orthopedics
                cardiovascular health, mortality, osteoarthritis, le8 score

                Comments

                Comment on this article