0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Aspectos histopatológicos da adenomiose em úteros bovinos nas diferentes fases do ciclo estral Translated title: Histophatological aspects of adenomyosis in bovine uteri in different phases of the estrous cycle

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Relacionaram-se as características da adenomiose com as fases do ciclo estral em 61 peças de úteros de bovinos colhidas em matadouros. A adenomiose foi classificada em superficial e profunda. A fase do ciclo estral foi estimada pela morfologia, pela coloração e pela vascularização do corpo lúteo e presença ou não de folículos ovarianos maiores que 8mm. Os animais que estavam em anestro (n=11) apresentaram a menor ocorrência de adenomiose (8,2%), e os que estavam na fase lútea média (n=21), a maior (31,0%). Nas fases lútea inicial (n=13) e folicular (n=16) as ocorrências foram semelhantes, 18,0 e 22,9%, respectivamente. A maior porcentagem de adenomiose profunda ocorreu nas fases lútea inicial e média, 45,0 e 47,4%, respectivamente, e durante o anestro e a fase folicular foram de 20,0 e 14,3%, respectivamente. Os resultados sugerem que a fase do ciclo estral influencia na ocorrência de adenomiose e no grau de infiltração miometrial das glândulas endometriais.

          Translated abstract

          The relationship of the adenomyosis characteristics and the phases of the estrus cycle in 61 cows bovine’s uteruses collected in slaughterhouses was studied. The adenomyoses were classified as superficial and deep. The morphology, staining and vascularization of the corpus luteum and the presence or not of larger ovarian follicles than 8mm helped to estimate tthe estrus cycle. The cows in anestrus (n=11) showed the least occurrence of adenomyosis (8.2%) and the animals in the medium luteal phase (n=21) the largest one(31,0%). In the initial luteal phase (n=13) and the follicular phase (n=16) the occurrences of adenomyosis were similar and equals to 18.0 and 22.9%, respectively. The largests percentage of deep adenomyosis were found in the initial and in the medium luteal phases, 45.0 and 47.4%, respectively, and during the anestrus and the follicular phase they were 20.0 and 14.3%, respectively. The data suggest that the cycle phase influences in adenomyosis occurrence and in the degree of miometrial infiltration of the endometrial glands.

          Related collections

          Most cited references19

          • Record: found
          • Abstract: found
          • Article: not found

          The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle.

          The ovary and uterus undergo extensive tissue remodeling throughout each reproductive cycle. This remodeling of the extracellular environment is dependent upon the cyclic hormonal changes associated with each estrous or menstrual cycle. In the ovary, tissue remodeling is requisite for growth and expansion of the follicle, breakdown of the follicular wall during the ovulatory process, transformation of the postovulatory follicle into the corpus luteum, as well as the structural dissolution of the corpus luteum during luteal regression. In the uterus, there is extraordinary turnover of the endometrial connective tissue matrix during each menstrual cycle. This turnover encompasses the complete breakdown and loss of this layer, followed by its subsequent regrowth. With implantation, extensive remodeling of the uterus occurs to support placentation. These dynamic changes in the ovarian and uterine extracellular architecture are regulated, in part, by the matrix metalloproteinase (MMP) system. The MMP system acts to control connective tissue remodeling processes throughout the body and is comprised of both a proteolytic component, the MMPs, and a regulatory component, the associated tissue inhibitors of metalloproteinases. The current review will highlight the key features of the MMPs and tissue inhibitors of metalloproteinases, focus on the changes and regulation of the MMP system that take place throughout the estrous and menstrual cycles, and address the impact of the dynamic tissue remodeling processes on ovarian and uterine physiology.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Adenomyosis: symptoms, histology, and pregnancy terminations.

            To correlate symptoms of uterine adenomyosis with histopathologic features.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Endothelial nitric oxide synthase in the endometrium during the menstrual cycle in patients with endometriosis and adenomyosis.

              To determine the expression of endothelial nitric oxide synthase in the endometrium during the menstrual cycle in endometriosis and adenomyosis. Immunohistochemical identification of endothelial nitric oxide in endometrial tissues using the monoclonal antibody. Department of obstetrics and gynecology in a university hospital. The subjects were divided into three groups: 35 patients with endometriosis, 33 patients with adenomyosis proven histologically, and 46 fertile controls. Semiquantitative immunostaining (evaluation nomogram) score in endometrial cells. The analyses revealed phase-dependent changes in the expression of endothelial nitric oxide synthase in the surface and glandular epithelia during the menstrual cycle in the fertile controls. The expression was weakest in the early proliferative phase, gradually increased, was most marked in the midsecretory phase, and decreased thereafter. In contrast, stromal cells did not change throughout the cycle. Contrary to expectations, the expression of endothelial nitric oxide synthase in endometriosis and adenomyosis was persistently greater than the control levels throughout the menstrual cycle. This study has shown that endothelial nitric oxide synthase is changed in a phase-dependent manner during the menstrual cycle. The exaggerated expression of endothelial nitric oxide synthase in the endometrium throughout the cycle suggests some pathologic role in endometriosis and adenomyosis.
                Bookmark

                Author and article information

                Journal
                abmvz
                Arquivo Brasileiro de Medicina Veterinária e Zootecnia
                Arq. Bras. Med. Vet. Zootec.
                Universidade Federal de Minas Gerais, Escola de Veterinária (Belo Horizonte, MG, Brazil )
                0102-0935
                1678-4162
                October 2007
                : 59
                : 5
                : 1097-1102
                Affiliations
                [01] Campos dos Goytacazes RJ orgnameUENF orgdiv1Centro de Ciências Agrárias e Tecnologias Agropecuárias
                Article
                S0102-09352007000500002 S0102-0935(07)05900502
                3d8f5b58-ef06-48f4-a2bb-4c5af58ede48

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 09 April 2007
                : 25 November 2007
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 19, Pages: 6
                Product

                SciELO Brazil

                Categories
                Medicina Veterinária

                bovine,histopathology,estrous cycle,adenomyosis,histopatologia,ciclo estral,adenomiose,bovino

                Comments

                Comment on this article