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      Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer

      Author(s): 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1 , 1
      Publication date (Electronic):
      Journal: New England Journal of Medicine
      Publisher: Massachusetts Medical Society

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          Abstract

          Among breast cancers without human epidermal growth factor receptor 2 (HER2) amplification, overexpression, or both, a large proportion express low levels of HER2 that may be targetable. Currently available HER2-directed therapies have been ineffective in patients with these "HER2-low" cancers.

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          Author and article information

          Contributors
          Journal
          Title: New England Journal of Medicine
          Abbreviated Title: N Engl J Med
          Publisher: Massachusetts Medical Society
          ISSN (Print): 0028-4793
          ISSN (Electronic): 1533-4406
          Publication date (Electronic): June 05 2022
          Affiliations
          [1 ]From the Memorial Sloan Kettering Cancer Center, New York (S.M.); Institut du Cancer de Montpellier, Université Montpellier, INSERM Unité 1194, Montpellier (W.J.), and Institut Curie, Université Paris Cité, Paris (J.-Y.P.) — both in France; Kanagawa Cancer Center, Yokohama (T.Y.), Kyushu Cancer Center, National Hospital Organization, Fukuoka (E.T.), Showa University Hospital, Tokyo (J.T.), and Tokai University School of Medicine, Isehara-shi (N.N.) — all in Japan; Yonsei Cancer Center, Yonsei University...
          Article
          DOI: 10.1056/NEJMoa2203690
          PubMed ID: 35665782
          SO-VID: 3d1b3dc9-f667-4052-8c6b-94645b419ee0
          Copyright © © 2022
          License:

          http://www.nejmgroup.org/legal/terms-of-use.htm

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