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      Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.

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          Abstract

          Reduced duration of antibiotic treatment might contain the emergence of multidrug-resistant bacteria in intensive care units. We aimed to establish the effectiveness of an algorithm based on the biomarker procalcitonin to reduce antibiotic exposure in this setting.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          Feb 06 2010
          : 375
          : 9713
          Affiliations
          [1 ] Service de Réanimation Médicale, Université Paris 7-Denis-Diderot, Hôpital Bichat-Claude-Bernard, Assistance Publique-Hôpitaux de Paris, Paris, France.
          Article
          S0140-6736(09)61879-1
          10.1016/S0140-6736(09)61879-1
          20097417
          3ce3e35b-a6be-4ef9-a9af-cc3a42dedaf2
          Copyright 2010 Elsevier Ltd. All rights reserved.
          History

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