For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
14
views
69
references
 Top references
cited by
4
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      206
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Antibiotic prophylaxis in open inguinal hernia repair: a literature review and summary of current knowledge

      review-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          More than 1 million inguinal hernia repairs are performed in Europe and the US annually. Although antibiotic prophylaxis is not required in clean, elective procedures, the routine use of implants (90% of inguinal hernia repairs are performed with mesh) makes the topic controversial. The European Hernia Society does not recommend routine antibiotic prophylaxis for elective inguinal hernia repairs. However, the latest randomized controlled trial, published by Mazaki et al., indicates that the use of prophylaxis is effective for the prevention of surgical site infection. Unnecessary prophylaxis contributes to the development of bacterial resistance and significantly increases healthcare costs. This review documents clinical trials on inguinal hernia repairs with mesh and summarizes the current knowledge. It also tries to solve certain problems, namely: what constitutes a real risk factor, late-onset infection, and how the “surgical environment” impacts on the need to use antibiotic prophylaxis.

          Related collections

          Most cited references69

          • Record: found
          • Abstract: found
          • Article: not found

          The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection.

          David C Classen, R Evans, Stanley Pestotnik … (1992)
          Randomized, controlled trials have shown that prophylactic antibiotics are effective in preventing surgical-wound infections. However, it is uncertain how the timing of antibiotic administration affects the risk of surgical-wound infection in actual clinical practice. We prospectively monitored the timing of antibiotic prophylaxis and studied the occurrence of surgical-wound infections in 2847 patients undergoing elective clean or "clean-contaminated" surgical procedures at a large community hospital. The administration of antibiotics 2 to 24 hours before the surgical incision was defined as early; that during the 2 hours before the incision, as preoperative; that during the 3 hours after the incision, as perioperative; and that more than 3 but less than 24 hours after the incision, as postoperative. Of the 1708 patients who received the prophylactic antibiotics preoperatively, 10 (0.6 percent) subsequently had surgical-wound infections. Of the 282 patients who received the antibiotics perioperatively, 4 (1.4 percent) had such infections (P = 0.12; relative risk as compared with the preoperatively treated group, 2.4; 95 percent confidence interval, 0.9 to 7.9). Of 488 patients who received the antibiotics postoperatively, 16 (3.3 percent) had wound infections (P less than 0.0001; relative risk, 5.8; 95 percent confidence interval, 2.6 to 12.3). Finally, of 369 patients who had antibiotics administered early, 14 (3.8 percent) had wound infections (P less than 0.0001; relative risk, 6.7; 95 percent confidence interval, 2.9 to 14.7). Stepwise logistic-regression analysis confirmed that the administration of antibiotics in the preoperative period was associated with the lowest risk of surgical-wound infection. We conclude that in surgical practice there is considerable variation in the timing of prophylactic administration of antibiotics and that administration in the two hours before surgery reduces the risk of wound infection.
          Article 0 comments Cited 175 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost.

            K Kirkland, D Sexton, Andrea Richardson … (2002)
            To measure the impact of orthopedic surgical-site infections (SSIs) on quality of life, length of hospitalization, and cost. A pairwise-matched (1:1) case-control study within a cohort. A tertiary-care university medical center and a community hospital. Cases of orthopedic SSIs were prospectively identified by infection control professionals. Matched controls were selected from the entire cohort of patients undergoing orthopedic surgery who did not have an SSI. Matching variables included type of surgical procedure, National Nosocomial Infections Surveillance risk index, age, date of surgery, and surgeon. Quality of life, duration of postoperative hospital stay, frequency of hospital readmission, overall direct medical costs, and mortality rate. Fifty-nine SSIs were identified. Each orthopedic SSI accounted for a median of 1 extra day of stay during the initial hospitalization (P = .001) and a median of 14 extra days of hospitalization during the follow-up period (P = .0001). Patients with SSI required more rehospitalizations (median, 2 vs 1; P = .0001) and more total surgical procedures (median, 2 vs 1; P = .0001). The median total direct cost of hospitalizations per infected patient was $24,344, compared with $6,636 per uninfected patient (P = .0001). Mortality rates were similar for cases and controls. Quality of life was adversely affected for patients with SSI. The largest decrements in scores on the Medical Outcome Study Short Form 36 questionnaire were seen in the physical functioning and role-physical domains. Orthopedic SSIs prolong total hospital stays by a median of 2 weeks per patient, approximately double rehospitalization rates, and increase healthcare costs by more than 300%. Moreover, patients with orthopedic SSIs have substantially greater physical limitations and significant reductions in their health-related quality of life.
            Article 0 comments Cited 167 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              The epidemiology of wound infection. A 10-year prospective study of 62,939 wounds.

              R Cruse, R Foord (1980)
              Article 0 comments Cited 91 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Wideochir Inne Tech Maloinwazyjne
                Journal ID (iso-abbrev): Wideochir Inne Tech Maloinwazyjne
                Journal ID (publisher-id): WIITM
                Title: Videosurgery and other Miniinvasive Techniques
                Publisher: Termedia Publishing House
                ISSN (Print): 1895-4588
                ISSN (Electronic): 2299-0054
                Publication date (Electronic): 05 October 2016
                Publication date (Print): 2016
                Volume: 11
                Issue: 3
                Pages: 127-136
                Affiliations
                [1 ]Regional Health Centre, Kartuzy, Poland
                [2 ]Department of Oncological Surgery, Medical University of Gdansk, Gdansk, Poland
                [3 ]Koscierzyna Specialist Hospital, Koscierzyna, Poland
                [4 ]Voivodeship Oncology Centre, Gdansk, Poland
                [5 ]Department of General Surgery, Hospital, Puck, Poland
                [6 ]2 [nd ] Department of Radiology, Medical University of Gdansk, Gdansk, Poland
                Author notes
                Address for correspondence Mateusz T. Zamkowski MD, Regional Health Centre, 7 Ceynowy St, 83-300 Kartuzy, Poland. phone: +48 504 236 036. e-mail: zamek@ 123456wp.eu
                Article
                Publisher ID: 28484
                DOI: 10.5114/wiitm.2016.62800
                PMC ID: 5095278
                PubMed ID: 27829934
                SO-VID: 3c1f6294-b00d-4a5b-ab32-bac9e99d7570
                Copyright © Copyright: © 2016 Fundacja Videochirurgii
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

                History
                Date received : 07 April 2016
                Date accepted : 26 September 2016
                Categories
                Subject: Review Paper

                Keywords: hernia,mesh repair,inguinal hernia repair,surgical site infection,antimicrobial prophylaxis,antibiotic prophylaxis
                Data availability:
                Keywords: hernia, mesh repair, inguinal hernia repair, surgical site infection, antimicrobial prophylaxis, antibiotic prophylaxis

                Comments

                Comment on this article

                scite_

                Similar content206

                See all similar

                Cited by4

                See all cited by

                Most referenced authors644

                See all reference authors