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N-acylsulfonamide assisted tandem C-H olefination/annulation: synthesis of isoindolinones.
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Abstract
A tandem C-H olefination/annulation sequence directed by N-acylsulfonamides affords a variety of isoindolinones. This transformation is compatible with aliphatic alkenes as well as conjugated alkenes. Notably, molecular oxygen can be used as the sole, eco-friendly oxidant.