iRGD-conjugated DSPE-PEG2000 nanomicelles for targeted delivery of salinomycin for treatment of both liver cancer cells and cancer stem cells.

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Abstract

To develop novel iRGD (internalizing Arg-Gly-Asp peptide)-conjugated DSPE-PEG2000 nanomicelles (M-SAL-iRGD) for delivery of salinomycin to both liver cancer cells and cancer stem cells (CSCs).

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Journal

Journal ID (iso-abbrev): Nanomedicine (Lond)

Title: Nanomedicine (London, England)

ISSN (Electronic): 1748-6963

ISSN (Print): 1743-5889

Publication date (Electronic): 2015

Volume: 10

Issue: 17

Affiliations

[1 ] Department of Pharmaceutical Sciences, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.

[2 ] School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fujian, China.

[3 ] International Joint Cancer Institute, Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.

Article

DOI: 10.2217/nnm.15.106

PubMed ID: 26355733

SO-VID: 3a2307d8-813a-4d92-8522-bbcacfafd90b

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Keywords: cancer nanotechnology,cancer stem cells,iRGD,liver cancer,micelles

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Keywords: cancer nanotechnology, cancer stem cells, iRGD, liver cancer, micelles

iRGD-conjugated DSPE-PEG2000 nanomicelles for targeted delivery of salinomycin for treatment of both liver cancer cells and cancer stem cells.

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RNA drug delivery

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