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Abstract
Mesoporous 58SiO(2)-(38-x)CaO-xMgO-4P(2)O(5) glasses (where x=0, 5, 10 and 20 mol%)
have been prepared by the sol-gel synthesis route. The effects of the substitution
of MgO for CaO on glass degradation and bioactivity were studied in tris-(hydroxymethyl)-aminomethane
and hydrochloric acid buffer solution (Tris-HCl) and simulated body fluid (SBF), respectively.
It is observed that the synthesized glasses with various MgO contents possess the
similar textural properties. The studies of in vitro degradability and bioactivity
show that the rate of glass degradation gradually decreases with the increase of MgO
and the formation of apatite layer on glass surface is retarded. The influences of
the composition upon glass properties are explained in terms of their internal structures.