Optical Fluorescence and Its Application to an Intravascular Blood Gas Monitoring System

In this article the development of fiber-optic sensors for biomedical applications is reviewed. Light-carrying fibers are potentially useful in oximetry, dye dilution measurements, laser-Doppler velocimetry, and fluorometry; as physical sensors of temperature, pressure, and radiation; and as chemical sensors of pH, partial pressure of blood gases, and glucose. Emphasis is placed on the principles and ideas used in the various devices rather than on detailed descriptions or critical discussions.