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      Disease externalities and net nutrition: Evidence from changes in sanitation and child height in Cambodia, 2005–2010

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          Highlights

          • Better sanitation accounts for Cambodia’s increase in child height from 2005 to 2010.

          • Sanitation improvements in regions over time are associated with height improvements.

          • Community open defecation matters more for child height than household open defecation.

          Abstract

          Child height is an important indicator of human capital and human development, in large part because early life health and net nutrition shape both child height and adult economic productivity and health. Between 2005 and 2010, the average height of children under 5 in Cambodia significantly increased. What contributed to this improvement? Recent evidence suggests that exposure to poor sanitation – and specifically to widespread open defecation – can pose a critical threat to child growth. We closely analyze the sanitation height gradient in Cambodia in these two years. Decomposition analysis, in the spirit of Blinder-Oaxaca, suggests that the reduction in children’s exposure to open defecation can statistically account for much or all of the increase in average child height between 2005 and 2010. In particular, we see evidence of externalities, indicating an important role for public policy: it is the sanitation behavior of a child’s neighbors that matters more for child height rather than the household’s sanitation behavior by itself. Moving from an area in which 100% of households defecate in the open to an area in which no households defecate in the open is associated with an average increase in height-for-age z-score of between 0.3 and 0.5. Our estimates are quantitatively robust and comparable with other estimates in the literature.

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          Wage Discrimination: Reduced Form and Structural Estimates

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            Growth faltering in rural Gambian infants is associated with impaired small intestinal barrier function, leading to endotoxemia and systemic inflammation.

            Growth faltering of rural Gambian infants is associated with a chronic inflammatory enteropathy of the mucosa of the small intestine that may impair both digestive/absorptive and barrier functions. The aim of this study was to determine whether the enteropathy was associated with a compromised barrier function that allowed translocation of antigenic macromolecules from the gut lumen into the body, with subsequent systemic immunostimulation, resulting in growth retardation. Rural Gambian infants were studied longitudinally at regular intervals between 8 and 64 wk of age. On each study day, each child was medically examined, anthropometric measurements were made, a blood sample was taken and an intestinal permeability test performed. Evidence of chronic immunostimulation was provided by abnormally elevated white blood cell, lymphocyte and platelet counts, and frequently raised plasma concentration of C-reactive protein. Intestinal permeability was abnormal and associated with impaired growth (r = -0.41, P < 0.001). Plasma concentrations of endotoxin and immunoglobulin (Ig)G-endotoxin core antibody were also elevated and related to both growth (r = -0.30, P < 0.02; r = -0.64, P < 0.0001, respectively) and measures of mucosal enteropathy. Plasma IgG, IgA and IgM levels increased rapidly with age toward adult concentrations. Raised values were related to poor growth but also to measures of mucosal enteropathy and the endotoxin antibody titer. The interrelationships among these variables and growth suggested that they were all part of the same growth-retarding mechanism. These data are consistent with the hypothesis of translocation of immunogenic lumenal macromolecules across a compromised gut mucosa, leading to stimulation of systemic immune/inflammatory processes and subsequent growth impairment.
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              Labor Market Discrimination Against Hispanic and Black Men

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                Author and article information

                Contributors
                Journal
                Econ Hum Biol
                Econ Hum Biol
                Economics and Human Biology
                Elsevier Science
                1570-677X
                1873-6130
                1 December 2016
                December 2016
                : 23
                : 235-245
                Affiliations
                [a ]Research Institute for Compassionate Economics
                [b ]World Bank Water and Sanitation Program East Asia and the Pacific, 113 Norodom Blvd, Phnom Penh, Cambodia
                [c ]Economics and Planning Unit, Indian Statistical Institute, New Delhi, India
                [d ]University of Texas, Austin, United States
                Author notes
                [* ]Corresponding author. sangita@ 123456riceinstitute.org
                Article
                S1570-677X(16)30148-4
                10.1016/j.ehb.2016.10.002
                5147726
                27776300
                393b77de-66d5-4ad1-9b02-ec8f9f3e1a01
                © 2016 The Authors

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 10 December 2015
                : 7 October 2016
                : 7 October 2016
                Categories
                Article

                height,early-life health,disease environment,sanitation,cambodia

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