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      Knowledge, Awareness, and Perception of COVID-19 and Artificial Intelligence: A Cross-Sectional Study Among the Population in Saudi Arabia

      research-article
      1 , , 2 , 3 , 4
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      Cureus
      Cureus
      survey, saudi arabia, machine learning, covid-19, artificial intelligence

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          Abstract

          Background: Artificial intelligence (AI) has made significant contributions to the development of medicines and vaccines. In addition, AI can analyze large amounts of COVID-19 test data, including the number of positive cases, to forecast the trajectory of the pandemic.

          Aim: This study aimed to assess the knowledge, perception, and awareness of the general population in Saudi Arabia regarding AI and its application in combating COVID-19.

          Methods: A cross-sectional research design was employed, and online surveys were distributed via email and social media platforms. Purposeful sampling was used to select participants who met the inclusion criteria. The reliability and validity of the survey instrument were also assessed.

          Results: The majority of respondents (34.6%) fell within the age range of 30 to 39 years. The sample predominantly consisted of female participants. Approximately 59% of respondents reported using at least one AI tool or application on a daily basis. Furthermore, the majority of respondents agreed that digital medical services, mentioned in a previous question, could be beneficial in reducing unnecessary interactions between patients and healthcare providers.

          Conclusion: The COVID-19 pandemic has demonstrated the transformative potential of AI in pandemic response. AI has played a crucial role in various aspects of combating COVID-19, including patient diagnosis, treatment development, and vaccine creation. However, challenges and limitations exist in terms of data accessibility, bias, and privacy when utilizing AI. These issues need to be addressed to ensure the ethical and responsible use of AI in the fight against COVID-19 and future pandemics.

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          Most cited references23

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          A pneumonia outbreak associated with a new coronavirus of probable bat origin

          Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats 1–4 . Previous studies have shown that some bat SARSr-CoVs have the potential to infect humans 5–7 . Here we report the identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China. The epidemic, which started on 12 December 2019, had caused 2,794 laboratory-confirmed infections including 80 deaths by 26 January 2020. Full-length genome sequences were obtained from five patients at an early stage of the outbreak. The sequences are almost identical and share 79.6% sequence identity to SARS-CoV. Furthermore, we show that 2019-nCoV is 96% identical at the whole-genome level to a bat coronavirus. Pairwise protein sequence analysis of seven conserved non-structural proteins domains show that this virus belongs to the species of SARSr-CoV. In addition, 2019-nCoV virus isolated from the bronchoalveolar lavage fluid of a critically ill patient could be neutralized by sera from several patients. Notably, we confirmed that 2019-nCoV uses the same cell entry receptor—angiotensin converting enzyme II (ACE2)—as SARS-CoV.
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            Rapid Identification of Potential Inhibitors of SARS‐CoV‐2 Main Protease by Deep Docking of 1.3 Billion Compounds

            Abstract The recently emerged 2019 Novel Coronavirus (SARS‐CoV‐2) and associated COVID‐19 disease cause serious or even fatal respiratory tract infection and yet no approved therapeutics or effective treatment is currently available to effectively combat the outbreak. This urgent situation is pressing the world to respond with the development of novel vaccine or a small molecule therapeutics for SARS‐CoV‐2. Along these efforts, the structure of SARS‐CoV‐2 main protease (Mpro) has been rapidly resolved and made publicly available to facilitate global efforts to develop novel drug candidates. Recently, our group has developed a novel deep learning platform – Deep Docking (DD) which provides fast prediction of docking scores of Glide (or any other docking program) and, hence, enables structure‐based virtual screening of billions of purchasable molecules in a short time. In the current study we applied DD to all 1.3 billion compounds from ZINC15 library to identify top 1,000 potential ligands for SARS‐CoV‐2 Mpro protein. The compounds are made publicly available for further characterization and development by scientific community.
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              Methodology Series Module 3: Cross-sectional Studies

              Cross-sectional study design is a type of observational study design. In a cross-sectional study, the investigator measures the outcome and the exposures in the study participants at the same time. Unlike in case–control studies (participants selected based on the outcome status) or cohort studies (participants selected based on the exposure status), the participants in a cross-sectional study are just selected based on the inclusion and exclusion criteria set for the study. Once the participants have been selected for the study, the investigator follows the study to assess the exposure and the outcomes. Cross-sectional designs are used for population-based surveys and to assess the prevalence of diseases in clinic-based samples. These studies can usually be conducted relatively faster and are inexpensive. They may be conducted either before planning a cohort study or a baseline in a cohort study. These types of designs will give us information about the prevalence of outcomes or exposures; this information will be useful for designing the cohort study. However, since this is a 1-time measurement of exposure and outcome, it is difficult to derive causal relationships from cross-sectional analysis. We can estimate the prevalence of disease in cross-sectional studies. Furthermore, we will also be able to estimate the odds ratios to study the association between exposure and the outcomes in this design.
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                Author and article information

                Journal
                Cureus
                Cureus
                2168-8184
                Cureus
                Cureus (Palo Alto (CA) )
                2168-8184
                25 June 2023
                June 2023
                : 15
                : 6
                : e40921
                Affiliations
                [1 ] Aesthetic and Restorative Dentistry, Riyadh Elm University, Riyadh, SAU
                [2 ] Restorative Dentistry, Jazan University, Jazan, SAU
                [3 ] Dentistry, King Saud University, Riyadh, SAU
                [4 ] Dentistry, Riyadh Elm University, Riyadh, SAU
                Author notes
                Article
                10.7759/cureus.40921
                10368304
                38f354b4-57c0-4fd9-83a9-b836f8f2a1d6
                Copyright © 2023, Haleem et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 16 April 2023
                : 19 June 2023
                Categories
                Dentistry

                survey,saudi arabia,machine learning,covid-19,artificial intelligence

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