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      Distribution of preoperative and postoperative astigmatism in a large population of patients undergoing cataract surgery in the UK

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          Abstract

          Purpose

          To assess the prevalence and severity of preoperative and postoperative astigmatism in patients with cataract in the UK.

          Setting

          Data from 8 UK National Health Service ophthalmology clinics using MediSoft electronic medical records (EMRs).

          Design

          Retrospective cohort study.

          Methods

          Eyes from patients aged ≥65 years undergoing cataract surgery were analysed. For all eyes, preoperative (corneal) astigmatism was evaluated using the most recent keratometry measure within 2 years prior to surgery. For eyes receiving standard monofocal intraocular lens (IOLs), postoperative refractive astigmatism was evaluated using the most recent refraction measure within 2–12 months postsurgery. A power vector analysis compared changes in the astigmatic 2-dimensional vector (J 0, J 45) before and after surgery, for the subgroup of eyes with both preoperative and postoperative astigmatism measurements. Visual acuity was also assessed preoperatively and postoperatively.

          Results

          Eligible eyes included in the analysis were 110 468. Of these, 78% (n=85 650) had preoperative (corneal) astigmatism ≥0.5 dioptres (D), 42% (n=46 003) ≥1.0 D, 21% (n=22 899) ≥1.5 D and 11% (n=11 651) ≥2.0 D. After surgery, the refraction cylinder was available for 39 744 (36%) eyes receiving standard monofocal IOLs, of which 90% (n=35 907) had postoperative astigmatism ≥0.5 D and 58% (n=22 886) ≥1.0 D. Visual acuity tended to worsen postoperatively with increased astigmatism (ρ=−0.44, P<0.01).

          Conclusions

          There is a significant burden of preoperative astigmatism in the UK cataract population. The available refraction data indicate that this burden is not reduced after surgery with implantation of standard monofocal IOLs. Measures should be taken to improve visual outcomes of patients with astigmatic cataract by simultaneously correcting astigmatism during cataract surgery.

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          Most cited references14

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          Effect of uncorrected astigmatism on vision.

          To examine the effect of uncorrected astigmatism in older adults. University vision clinic. Investigational simulation. Healthy adult presbyopes had astigmatism of 0.00 to -4.00 diopters cylinder (DC) × 90 degrees and -3.00 DC × 90, × 180, and × 45 degrees induced with spectacle lenses, with the mean spherical equivalent compensated to plano, in random order. Visual acuity was assessed binocularly using a computerized test chart at 95%, 50%, and 10% contrast. Near acuity and reading speed were measured using standardized reading texts. Light scatter was quantified with a C-Quant straylight meter and driving reaction times with a computer simulator. Visual clarity of a mobile phone and computer screen was subjectively rated. Distance visual acuity in the 21 volunteers decreased with increasing uncorrected astigmatic power (F = 174.50, P .05); however, the reliability and variability of measurements decreased with increasing uncorrected astigmatic power (P .05), although subjective rating of clarity decreased with increasing uncorrected astigmatic power (P < .001). Uncorrected astigmatism at the 45-degree or 180-degree orientation resulted in worse distance and near visual acuity and subjective-rated clarity than at the 90-degree orientation (P < .05). Uncorrected astigmatism, even as low as 1.00 D, caused significantly decreased vision and if left uncorrected could significantly affect patients' independence, quality of life, and well-being. Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
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            The Cataract National Dataset electronic multi-centre audit of 55,567 operations: updating benchmark standards of care in the United Kingdom and internationally.

            To pilot the use of the Cataract National Dataset (CND) using multi-centre data from Electronic Patient Record (EPR) systems and to demonstrate the ability of the CND to deliver certain of its intended benefits, including detailed preoperative profiling of cataract surgery patients and updating of benchmark standards of care in the NHS and beyond. NHS departments using EPR systems to collect a minimum preoperative, anaesthetic, operative and postoperative data set, the CND, were invited to submit data, which were remotely extracted, anonymised, assessed for conformity and completeness, and analysed. Four-hundred and six surgeons from 12 NHS Trusts submitted data on 55,567 cataract operations between November 2001 and July 2006 (86% from January 2004). Mean age (SD) was 75.4 (10.4) years, 62.0% female. Surgery was for first eyes in 58.5%, under local anaesthesia in 95.5% and by phacoemulsification in 99.7%. Trainees performed 33.9% of operations. Preoperative visual acuity (VA) was 6/12 or better in 42.9% eyes overall, in 35.3% first eyes and in 55.3% second eyes. Complication rates included the following: posterior capsule rupture and/or vitreous loss of 1.92%, simple zonule dialysis of 0.46% and retained lens fragments of 0.18%. Postoperative VA of 6/12 or better (and 6/6 or better) was achieved for 91.0% (45.9%) of all eyes, 94.7% (51.0%) of eyes with no co-pathologies and 79.9% (30.2%) of eyes with one or more co-pathologies respectively. The CND is fit for purpose, is able to deliver useful benefits and can be collected as part of routine clinical care via EPR systems. This survey confirms shifts in practice since the 1997-1998 UK National Survey with full conversion to phacoemulsification, better preoperative acuity, a halving of the surgical 'index' benchmark complication of posterior capsule rupture and/or vitreous loss, and improved VA outcomes.
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              Power vector analysis of the optical outcome of refractive surgery

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                Author and article information

                Journal
                Br J Ophthalmol
                Br J Ophthalmol
                bjophthalmol
                bjo
                The British Journal of Ophthalmology
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                0007-1161
                1468-2079
                July 2019
                6 September 2018
                : 103
                : 7
                : 993-1000
                Affiliations
                [1 ] departmentThe NIHR Biomedical Research Centre , Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology , London, UK
                [2 ] departmentCataract Service , Moorfields Eye Hospital , London, UK
                [3 ] Alcon Laboratories Inc , Fort Worth, Texas, USA
                [4 ] Alcon Management SA , Geneva, Switzerland
                [5 ] departmentCentre of Excellence for Retrospective Studies , IQVIA , London, UK
                [6 ] departmentOphthalmology , University Hospital Southampton NHS Foundation Trust , Southampton, UK
                [7 ] departmentOphthalmology , University of Southampton , Southampton, UK
                Author notes
                [Correspondence to ] David F Anderson, QuintilesIMS, London KT16 8EH, UK; davidanderson3@ 123456nhs.net
                Article
                bjophthalmol-2018-312025
                10.1136/bjophthalmol-2018-312025
                6591741
                30190365
                38478c5f-1bb8-434f-a657-46fadfab1d54
                © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 05 February 2018
                : 17 July 2018
                : 07 August 2018
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/100009010, Novartis Pharmaceuticals UK Limited;
                Categories
                Clinical Science
                1506
                Custom metadata
                unlocked

                Ophthalmology & Optometry
                angle,epidemiology,treatment other,vision
                Ophthalmology & Optometry
                angle, epidemiology, treatment other, vision

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