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      COVID-19 vaccine hesitancy amongst healthcare workers: An assessment of its magnitude and determinants during the initial phase of national vaccine deployment in Nigeria

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          Abstract

          Background

          While vaccination plays a critical role in the global response to the COVID-19 pandemic, vaccine rollout remains suboptimal in Nigeria and other Low- and Middle-income countries (LMICs). This study documents the level of hesitancy among health workers (HWs) during the initial COVID-19 vaccine deployment phase in Nigeria and assesses the magnitude and determinants of hesitancy across Nigeria.

          Methods

          A cross sectional study across all States in Nigeria was conducted with over 10,000 HWs interviewed between March and April 2021. Data were cleaned and analyzed with proportions and confidence intervals of hesitancy documented and stratification by HW category. We compared the level of confidence/acceptance to be vaccinated across Nigeria and documented the sources of negative information amongst HWs who refused the vaccine.

          Findings

          Among the 10 184 HWs interviewed, 9 369 [92% (95% CI= 91, 92)] were confident of the COVID-19 vaccines and were already vaccinated at the time of this survey. Compared to HWs who were less than 20 years old, those aged 50 – 59 years were significantly more confident of the COVID-19 vaccines and had been vaccinated (OR=3.8, 95% CI=2.3 – 6.4, p<0.001). Only 858 (8%) of the HWs interviewed reported being hesitant with 57% (479/858) having received negative information, with the commonest source of information from social media (43.4%.)

          Interpretation

          A vast majority of HWs who were offered COVID-19 vaccines as part of the first phase of national vaccine roll out were vaccinated and reported being confident of the COVID-19 vaccines. The reported hesitancy was due mainly to safety issues, and negative information about vaccines from social media. The issues identified remain a significant risk to the success of subsequent phases of the vaccine rollout in Nigeria.

          Funding

          None.

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          Most cited references23

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          A global survey of potential acceptance of a COVID-19 vaccine

          Several coronavirus disease 2019 (COVID-19) vaccines are currently in human trials. In June 2020, we surveyed 13,426 people in 19 countries to determine potential acceptance rates and factors influencing acceptance of a COVID-19 vaccine. Of these, 71.5% of participants reported that they would be very or somewhat likely to take a COVID-19 vaccine, and 61.4% reported that they would accept their employer’s recommendation to do so. Differences in acceptance rates ranged from almost 90% (in China) to less than 55% (in Russia). Respondents reporting higher levels of trust in information from government sources were more likely to accept a vaccine and take their employer’s advice to do so.
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            Is Open Access

            Acceptability of Vaccination Against COVID-19 Among Healthcare Workers in the Democratic Republic of the Congo

            Purpose This study aims to estimate the acceptability of a future vaccine against COVID-19 and associated factors if offered in Congolese health-care workers (HCWs), since they have the highest direct exposure to the disease. Patients and Methods We conducted an analytical cross-sectional study among 23 Congolese referral hospitals, including three university hospitals, located in three towns from March through 30 April 2020. The main outcome variable was healthcare workers’ acceptance of a future vaccine against COVID-19. The associated factors of vaccination willingness were identified through a logistic regression analysis. Results A sample of 613 HCWs participated in the study and completed the study questionnaire, including 312 (50.9%) men and 301 (49.1%) women. Only 27.7% of HCWs said that they would accept a COVID-19 vaccine if it was available. From the logistic regression analysis, male healthcare workers (ORa=1.17, 95% CI: 1.15–2.60), primarily doctors (ORa=1.59; 95% CI:1.03–2.44) and having a positive attitude towards a COVID-19 vaccine (ORa=11.49; 95% CI: 5.88–22.46) were significantly associated with reporting willingness to be vaccinated. Conclusion For acceptability of vaccination against COVID-19 among others education among HCWs is crucial because health professionals’ attitudes about vaccines are an important determinant of their own vaccine uptake and their likelihood of recommending the vaccine to their patients.
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              Is Open Access

              Attitudes of healthcare workers towards COVID-19 vaccination: a survey in France and French-speaking parts of Belgium and Canada, 2020

              In October and November 2020, we conducted a survey of 2,678 healthcare workers (HCWs) involved in general population immunisation in France, French-speaking Belgium and Quebec, Canada to assess acceptance of future COVID-19 vaccines (i.e. willingness to receive or recommend these) and its determinants. Of the HCWs, 48.6% (n = 1,302) showed high acceptance, 23.0% (n = 616) moderate acceptance and 28.4% (n = 760) hesitancy/reluctance. Hesitancy was mostly driven by vaccine safety concerns. These must be addressed before/during upcoming vaccination campaigns.
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                Author and article information

                Journal
                eClinicalMedicine
                EClinicalMedicine
                eClinicalMedicine
                Published by Elsevier Ltd.
                2589-5370
                25 June 2022
                August 2022
                25 June 2022
                : 50
                : 101499
                Affiliations
                [a ]World Health Organization Country office, Abuja, Nigeria
                [b ]MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia
                [c ]Department of Strategic Information, Institute of Human Virology, Abuja, Nigeria
                [d ]National Primary Health Care Development Agency (NPHCDA) Abuja, Nigeria
                [e ]World Health Organization East and Southern Africa Inter country support team (IST), Harare, Zimbabwe
                [f ]Africa Disease prevention and research development Initiative (ADRAP), Abuja, Nigeria
                [g ]University of Abuja Teaching Hospital, Abuja, Nigeria
                Author notes
                [* ]Corresponding author at: Terna Nomhwange, World Health Organization Country office, Abuja, Nigeria.
                [1]

                Contributed equally.

                Article
                S2589-5370(22)00229-2 101499
                10.1016/j.eclinm.2022.101499
                9233171
                35770256
                3796ecc3-2d24-4f4a-86d0-37eb5d8e0086
                © 2022 Published by Elsevier Ltd.

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

                History
                : 14 January 2022
                : 19 May 2022
                : 20 May 2022
                Categories
                Articles

                covid-19 vaccine,vaccine hesitancy,health workers,nigeria

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