For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
19
views
27
references
 Top references
cited by
11
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      312
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Epidural Hematoma Related with Low-Dose Aspirin : Complete Recovery without Surgical Treatment

      case-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Hemorrhagic complications associated with aspirin use occur primarily at skin or gastrointestinal sites but can occasionally occur in the central nervous system. In particular, spontaneous spinal epidural hemorrhage (SSEH) associated with aspirin is very rare. We report a case of low-dose (100 mg daily) aspirin-related SSEH that was successfully treated with medical management. Our case indicates that low-dose aspirin could induce SSEH and that conservative treatment with close observation and repeated imaging studies should be considered in cases with neurological improvement or mild deficits.

          Related collections

          Most cited references27

          • Record: found
          • Abstract: found
          • Article: not found

          Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study.

          H D Lewis, J W Davis, D G Archibald … (1983)
          We conducted a multicenter, double-blind, placebo-controlled randomized trial of aspirin treatment (324 mg in buffered solution daily) for 12 weeks in 1266 men with unstable angina (625 taking aspirin and 641 placebo). The principal end points were death and acute myocardial infarction diagnosed by the presence of creatine kinase MB or pathologic Q-wave changes on electrocardiograms. The incidence of death or acute myocardial infarction was 51 per cent lower in the aspirin group than in the placebo group: 31 patients (5.0 per cent) as compared with 65 (10.1 per cent); P = 0.0005. Nonfatal acute myocardial infarction was 51 per cent lower in the aspirin group: 21 patients (3.4 per cent) as compared with 44 (6.9 per cent); P = 0.005. The reduction in mortality in the aspirin group was also 51 per cent--10 patients (1.6 per cent) as compared with 21 (3.3 per cent)--although it was not statistically significant; P = 0.054. There was no difference in gastrointestinal symptoms or evidence of blood loss between the treatment and control groups. Our data show that aspirin has a protective effect against acute myocardial infarction in men with unstable angina, and they suggest a similar effect on mortality.
          Article 0 comments Cited 95 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Spontaneous spinal epidural hematoma: analysis of 23 cases.

            Zhan Liu, Qingfang Jiao, Jianguo Xu … (2008)
            Spontaneous spinal epidural hematoma is a rare but disabling disease. To explore its characters and find out what factors influence the prognosis, we gave a retrospective analysis of 23 patients in our department in the past 8 years. Spontaneous spinal epidural hematoma was diagnosed by taking MRIs of patients without surgical management or by histopathological examination. We registered patient's case history, laboratory examination, radiological image, treatment, pathological result, and prognosis after 3 months and gave them nonparameter analysis. Primary neurological status and progressive intervals have correlation with prognosis (P< .01), and the latter less than 12 hours predict worse prognosis (P= .032). Spinal edema in MRI predicts pessimistic prognosis (P= .013). Long hematoma predicts worse prognosis (P= .02). Preoperative interval, emphasized by other authors, has no statistical correlation with prognosis in this study (P= .832). Finally, patients with a single hematoma or hematoma mingled with other spinal disturbance have the same prognosis (P= .065). The primary neurological status, progressive interval, spinal edema, and size of hematoma will influence the prognosis of the patient with SSEH. The major treatment is surgical intervention, and it should be operated as soon as possible to avoid the aggravation of neurological status. Conservative treatment is not considered unless patient's neurological deficiency has relieved in the early period.
            Article 0 comments Cited 41 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?

              Erica Warner, J. F. Mitchell (2002)
              Article 0 comments Cited 33 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): J Korean Neurosurg Soc
                Journal ID (iso-abbrev): J Korean Neurosurg Soc
                Journal ID (publisher-id): JKNS
                Title: Journal of Korean Neurosurgical Society
                Publisher: The Korean Neurosurgical Society
                ISSN (Print): 2005-3711
                ISSN (Electronic): 1598-7876
                Publication date (Print): May 2012
                Publication date (Electronic): 31 May 2012
                Volume: 51
                Issue: 5
                Pages: 308-311
                Affiliations
                [1 ]Department of Neurosurgery, Kyungpook National University Hospital, Daegu, Korea.
                [2 ]Department of Neurology, College of Medicine, Chung-Ang University, Seoul, Korea.
                [3 ]Department of Neurosurgery, Spine Center, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon, Korea.
                Author notes
                Address for reprints: Suk-Hyung Kang, M.D. Department of Neurosurgery, Spine Center, Chuncheon Sacred Heart Hospital, Hallym University, 77 Sakju-ro, Chuncheon 200-704, Korea. Tel : +82-33-240-5173, Fax : +82-33-255-6244, nscharisma@ 123456hanmail.net
                Article
                DOI: 10.3340/jkns.2012.51.5.308
                PMC ID: 3393869
                PubMed ID: 22792431
                SO-VID: 3704689d-c37c-47d8-b4ae-f0977b83c102
                Copyright © Copyright © 2012 The Korean Neurosurgical Society
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 02 August 2011
                Date revision received : 06 February 2012
                Date accepted : 15 May 2012
                Categories
                Subject: Case Report

                ScienceOpen disciplines: Surgery
                Keywords: spinal epidural hematoma,aspirin,medical management
                Data availability:
                ScienceOpen disciplines: Surgery
                Keywords: spinal epidural hematoma, aspirin, medical management

                Comments

                Comment on this article

                scite_

                Similar content312

                See all similar

                Cited by11

                See all cited by

                Most referenced authors270

                See all reference authors