Glypican-3 and KRT19 are markers associating with metastasis and poor prognosis of pancreatic ductal adenocarcinoma.

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Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor with metastasis in most patients at diagnosis. The molecular mechanisms associated with its high malignancy have not been fully elucidated. This study investigated the clinicopathological significances of GPC3 and KRT19 expression in PDAC.

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Author and article information

Journal

Journal ID (iso-abbrev): Cancer Biomark

Title: Cancer biomarkers : section A of Disease markers

Publisher: IOS Press

ISSN (Electronic): 1875-8592

ISSN (Print): 1574-0153

Publication date (Electronic): 2016

Volume: 17

Issue: 4

Affiliations

[1 ] Department of General Surgery, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

[2 ] Research Laboratory of Hepatobiliary Diseases, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

[3 ] Department of Pathology, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

[4 ] Department of Pathology, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Article

Publisher Item ID: CBM655

DOI: 10.3233/CBM-160655

PubMed ID: 27689616

SO-VID: 36640ecf-cc3c-4744-9ab3-78f1fbd51c7e

History

Keywords: GPC3,CA19-9,KRT19,Pancreatic ductal adenocarcinoma,dysplasia,immunohistochemistry,pancreatic intraepithelial neoplasia

Data availability:

Keywords: GPC3, CA19-9, KRT19, Pancreatic ductal adenocarcinoma, dysplasia, immunohistochemistry, pancreatic intraepithelial neoplasia

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