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      Efficacy and safety of baloxavir marboxil versus neuraminidase inhibitors in the treatment of influenza virus infection in high-risk and uncomplicated patients - a Bayesian network meta-analysis.

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          Abstract

          Previous network meta-analysis (NMA) demonstrated advantageous or similar efficacy of baloxavir marboxil (baloxavir) over neuraminidase inhibitors in otherwise healthy (OwH) influenza patients. This analysis assessed the efficacy and safety of baloxavir in the subgroup of high-risk (HR) patients and in the population of uncomplicated influenza consisting of OwH and HR patients with influenza.

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          Author and article information

          Journal
          Curr Med Res Opin
          Current medical research and opinion
          Informa UK Limited
          1473-4877
          0300-7995
          February 2021
          : 37
          : 2
          Affiliations
          [1 ] Creativ-Ceutical, London, UK.
          [2 ] Medical Affairs, Shionogi & Co., Ltd., Osaka, Japan.
          [3 ] Creativ-Ceutical, Krakow, Poland.
          [4 ] Creativ-Ceutical, Rotterdam, Netherlands.
          [5 ] Global Market Access, Shionogi Limited, London, UK.
          [6 ] Hirotsu Clinic, Kanagawa, Japan.
          Article
          10.1080/03007995.2020.1839400
          33079575
          35f55c80-0997-4811-ab57-4e5b93bbf500
          History

          Network meta-analysis,baloxavir,high-risk patients,influenza

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