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      Is Open Access

      Quality assurance in proton beam therapy using a plastic scintillator and a commercially available digital camera

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          Abstract

          Purpose

          In this article, we evaluate a plastic scintillation detector system for quality assurance in proton therapy using a BC‐408 plastic scintillator, a commercial camera, and a computer.

          Methods

          The basic characteristics of the system were assessed in a series of proton irradiations. The reproducibility and response to changes of dose, dose‐rate, and proton energy were determined. Photographs of the scintillation light distributions were acquired, and compared with Geant4 Monte Carlo simulations and with depth‐dose curves measured with an ionization chamber. A quenching effect was observed at the Bragg peak of the 60 MeV proton beam where less light was produced than expected. We developed an approach using Birks equation to correct for this quenching. We simulated the linear energy transfer ( LET) as a function of depth in Geant4 and found Birks constant by comparing the calculated LET and measured scintillation light distribution. We then used the derived value of Birks constant to correct the measured scintillation light distribution for quenching using Geant4.

          Results

          The corrected light output from the scintillator increased linearly with dose. The system is stable and offers short‐term reproducibility to within 0.80%. No dose rate dependency was observed in this work.

          Conclusions

          This approach offers an effective way to correct for quenching, and could provide a method for rapid, convenient, routine quality assurance for clinical proton beams. Furthermore, the system has the advantage of providing 2D visualization of individual radiation fields, with potential application for quality assurance of complex, time‐varying fields.

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          Most cited references24

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          Tolerances for the accuracy of photon beam dose calculations of treatment planning systems.

          To design a consistent set of criteria for acceptability of photon beam dose calculations of treatment planning systems. The set should be applicable in combination with a test package used for evaluation of a treatment planning system, such as the ones proposed by the AAPM Task Group 23 or by the Netherlands Commission on Radiation Dosimetry. Tolerances have been defined for the accuracy with which a treatment planning system should be able to calculate the dose in different parts of a photon beam: the central beam axis and regions with large and small dose gradients. For increasing complexity of the geometry, wider tolerances are allowed, varying between 2 and 5%. For the evaluation of a large number of data points an additional quantity, the confidence limit, has been introduced, which combines the influence of systematic and random deviations. The proposed tolerances have been compared with other recommendations for a number of clinically relevant examples, showing considerable differences, which are partly due to the way the complexity of the geometry is taken into account. Furthermore differences occur if criteria for acceptability of dose calculations are related either to the local dose value or to a normalized dose value. Although it is acknowledged that the general aim must be to have good agreement between dose calculation and the actual dose value, e.g. within 2% or 2 mm, current day algorithms and their implementation into commercial treatment planning systems result often in larger deviations. A high accuracy can at present only be achieved in relatively simple cases. The new set of tolerances and the quantity confidence limit have proven to be useful tools for the acceptance of photon beam dose calculation algorithms of treatment planning systems.
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            Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code.

            The motivation of this study was to find and eliminate the cause of errors in dose-averaged linear energy transfer (LET) calculations from therapeutic protons in small targets, such as biological cell layers, calculated using the geant 4 Monte Carlo code. Furthermore, the purpose was also to provide a recommendation to select an appropriate LET quantity from geant 4 simulations to correlate with biological effectiveness of therapeutic protons.
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              Hadrontherapy: a Geant4-Based Tool for Proton/Ion-Therapy Studies

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                Author and article information

                Contributors
                adam.gibson@ucl.ac.uk
                Journal
                J Appl Clin Med Phys
                J Appl Clin Med Phys
                10.1002/(ISSN)1526-9914
                ACM2
                Journal of Applied Clinical Medical Physics
                John Wiley and Sons Inc. (Hoboken )
                1526-9914
                29 July 2017
                September 2017
                : 18
                : 5 ( doiID: 10.1002/acm2.2017.18.issue-5 )
                : 210-219
                Affiliations
                [ 1 ] University College London Medical Physics and Biomedical Engineering London UK
                [ 2 ] Clatterbridge Cancer Centre Medical Physics and Biomedical Engineering London UK
                Author notes
                [*] [* ] Author to whom correspondence should be addressed. Adam Gibson

                E‐mail: adam.gibson@ 123456ucl.ac.uk

                Article
                ACM212143
                10.1002/acm2.12143
                5874858
                28755419
                34dce784-ba77-427f-aa11-3e3d7724dbe9
                © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 12 January 2017
                : 14 May 2017
                : 14 June 2017
                Page count
                Figures: 9, Tables: 1, Pages: 10, Words: 6133
                Funding
                Funded by: King Abdulaziz City for Science and Technology (KACST) (Saudi Arabia)
                Categories
                87.53.Bn
                87.53.Jw
                87.55.Qr
                Radiation Oncology Physics
                Radiation Oncology Physics
                Custom metadata
                2.0
                acm212143
                September 2017
                Converter:WILEY_ML3GV2_TO_NLMPMC version:version=5.3.4 mode:remove_FC converted:29.03.2018

                proton therapy,quality assurance,radiotherapy
                proton therapy, quality assurance, radiotherapy

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