- Record: found
- Abstract: found
- Article: not found
The ginsenoside metabolite compound K exerts its anti-inflammatory activity by downregulating memory B cell in adjuvant-induced arthritis.
Jingyu Chen
1 ,
Qingtong Wang
1 ,
Huaxun Wu
1 ,
Kangkang Liu
1 ,
Yujing Wu
1 ,
Yan Chang
1 ,
Wei Wei
1
Jul 2016
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Compound K (CK, 20-O-d-glucopyranosyl-20(S)-protopanaxadiol), a novel ginsenoside metabolite, is structurally a member of the dammarane-type triterpene saponins. Several studies have identified the anti-inflammatory activity of CK. Our previous study demonstrated that CK exerted its anti-inflammatory effect via inhibition of abnormal activation and differentiation of T cells. However, its mechanism of action on B cells remains unclear.