Association between GH receptor polymorphism (exon 3 deletion), serum IGF1, semen quality, and reproductive hormone levels in 838 healthy young men.

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Abstract

GH activity may be involved in male reproductive function. A common genetic polymorphism in the gene encoding the GH receptor (GHR) results in deletion of the entire exon 3 sequence (GHRd3 isoform). The short GHRd3/d3 isoform seems more sensitive compared with full-length receptors (GHRfl/fl).

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Author and article information

Journal

Journal ID (iso-abbrev): Eur. J. Endocrinol.

Title: European journal of endocrinology

Publisher: Bioscientifica

ISSN (Electronic): 1479-683X

ISSN (Print): 0804-4643

Publication date (Electronic): Apr 2014

Volume: 170

Issue: 4

Affiliations

[1 ] Department of Growth and Reproduction GR, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Rigshospitalet Section 5064, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.

Article

Publisher Item ID: EJE-13-0729

DOI: 10.1530/EJE-13-0729

PubMed ID: 24412931

SO-VID: 332f5f3a-6558-4c1b-b329-b70a47c3e03d

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