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      Cáncer papilar primario en quiste del conducto tirogloso: A propósito de un caso

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          Abstract

          El conducto tirogloso es una anomalía congénita resultado de la retención del tracto epitelial entre la tiroides, el foramen cecum y el piso de la faringe. La aparición de un carcinoma en el quiste del conducto tirogloso es rara. Hasta donde sabemos se han publicado 150 casos en la literatura internacional. Presentamos un caso de carcinoma papilar en un quiste del conducto tirogloso tratado en nuestra institución, el cual representa el único caso tratado en nuestro departamento en un período de 17 años.

          Translated abstract

          A thyroglossal duct cyst is a congenital anomaly resulting from retention of an epithelial tract between the thyroid and the foramen cecum, at the floor of the pharynx. Papillary carcinoma originating in a thyroglossal duct cyst is a rare event. As far as we know, only 150 cases of thyroglossal duct cyst carcinoma have been reported in the international literature. We present one case of pa-pillary carcinoma arising in a thyroglossal duct cyst treated at our institution. This is the first case managed by our department in seventeen years.

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          Thyroglossal duct carcinoma: a rational approach to management.

          To discuss the authors' experience with thyroglossal duct carcinoma and present a rational approach to the management of this entity. A retrospective review of the cytopathology and pathology records of all patients with the diagnosis of a thyroglossal duct remnant from 1965 to 1997 was performed. Three cases of papillary thyroglossal duct carcinoma were identified, with one suspected squamous cell carcinoma by needle aspiration. The papillary carcinomas are discussed in detail to illustrate the difficulty encountered in managing the thyroid gland in the setting of a thyroglossal duct carcinoma. Fine-needle aspiration proved effective in making the diagnosis preoperatively. The authors recommend that a thyroglossal duct cyst with a microscopic focus of papillary carcinoma, without cyst wall invasion, be managed with a Sistrunk procedure. Treatment of all other thyroglossal duct papillary carcinomas should include removal of all thyroid tissue followed by radioactive iodine treatment.
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            Cytologic findings in thyroglossal duct carcinoma.

            Approximately 150 cases of thyroglossal duct carcinoma, predominantly of the papillary type, have been reported, but the preoperative fine-needle aspiration (FNA) diagnosis of such neoplasms has rarely been cited. The authors describe FNA findings in four samples obtained from three patients who were 29, 50, and 83 years of age, histologically diagnosed as papillary (n = 2) and squamous (n = 1) thyroglossal duct carcinomas. Atypia and squamous cell carcinoma were the FNA diagnoses in the patients with papillary carcinomas. The remaining case was correctly diagnosed as keratinizing squamous cell carcinoma. Cellularity was scant in two cases and moderate in one, and all displayed a cystic background. The authors also reviewed FNA features in 11 papillary and 2 Hurthle cell carcinomas from the English language literature; diagnostic findings were present in less than one third of the cases. In conclusion, familiarity with the FNA findings of thyroglossal duct carcinoma is limited by its rarity. The presence of large, atypical squamous cells, or psammoma bodies, in the FNA material of a midline anterior cystic neck mass should suggest papillary thyroglossal duct carcinoma.
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              Thyroglossal duct carcinoma.

              Primary carcinoma of the thyroglossal duct is rare. This discussion reports two cases and reviews the 50 previously reported in the literature. The criteria for diagnosis include evidence of a thyroglossal duct remnant and a normal thyroid gland. The differentiation from cystic metastases to lymph nodes is pointed out. The histologic types parallel those of carcinoma of the thyroid gland, papillary carcinoma being the most common and having a generally favorable prognosis. The clinical presentation of these tumors is similar to that with benign cysts and thus is of limited value in the diagnosis.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                rvo
                Revista Venezolana de Oncología
                Rev. venez. oncol.
                Casa publicadora Ateproca C.A (Caracas )
                0798-0582
                March 2006
                : 18
                : 1
                : 49-53
                Affiliations
                [1 ] INSTITUTO DE ONCOLOGÍA DR. MIGUEL PÉREZ CARREÑO
                [2 ] INSTITUTO DE ONCOLOGÍA DR. MIGUEL PÉREZ CARREÑO VENEZUELA
                Article
                S0798-05822006000100009
                31ef3a49-fbf2-44d4-9ad0-ffb5842d4068

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Venezuela

                Self URI (journal page): http://www.scielo.org.ve/scielo.php?script=sci_serial&pid=0798-0582&lng=en
                Categories
                ONCOLOGY

                Oncology & Radiotherapy
                Cancer,papillary carcinoma,thyroglossal cyst,thyroids,treatment,surgery,Cáncer,carcinoma papilar,quiste tirogloso,tiroides,tratamiento, cirugía

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