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      UTE imaging with simultaneous water and fat signal suppression using a time-efficient multispoke inversion recovery pulse sequence : Optimized Method for Long T2 Signal Suppression

      1 , 2 , 2
      Magnetic Resonance in Medicine
      Wiley

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          Abstract

          The long repetition time and inversion time with inversion recovery preparation ultrashort echo time (UTE) often causes prohibitively long scan times. We present an optimized method for long T2 signal suppression in which several k-space spokes are acquired after each inversion preparation.

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          Most cited references9

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          Design and analysis of a practical 3D cones trajectory.

          The 3D Cones k-space trajectory has many desirable properties for rapid and ultra-short echo time magnetic resonance imaging. An algorithm is presented that generates the 3D Cones gradient waveforms given a desired field of view and resolution. The algorithm enables a favorable trade-off between increases in readout time and decreases in the total number of required readouts. The resulting trajectory is very signal-to-noise ratio (SNR) efficient and has excellent aliasing properties. A rapid high-resolution ultra-short echo time imaging sequence is used to compare the 3D Cones trajectory to 3D projection reconstruction (3DPR) sampling schemes. For equivalent scan times, the 3D Cones trajectory has better SNR performance and fewer aliasing artifacts as compared to the 3DPR trajectory. Magn Reson Med, 2006. (c) 2006 Wiley-Liss, Inc.
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            MR properties of brown and white adipose tissues.

            To explore the MR signatures of brown adipose tissue (BAT) compared with white adipose tissue (WAT) using single-voxel MR spectroscopy. (1) H MR STEAM spectra were acquired from a 3 Tesla clinical whole body scanner from seven excised murine adipose tissue samples of BAT (n=4) and WAT (n=3). Spectra were acquired at multiple echo times (TEs) and inversion times (TIs) to measure the T1, T2, and T2-corrected peak areas. A theoretical triglyceride model characterized the fat in terms of number of double bonds (ndb) and number of methylene-interrupted double bonds (nmidb). Negligible differences between WAT and BAT were seen in the T1 and T2 of fat and the T2 of water. However, the water fraction in BAT was higher (48.5%) compared with WAT (7.1%) and the T1 of water was lower in BAT (618 ms) compared with WAT (1053 ms). The fat spectrum also differed, indicating lower levels of unsaturated triglycerides in BAT (ndb=2.7, nmidb=0.7) compared with WAT (ndb=3.3, nmidb=1.0). We have demonstrated that there are several key MR-based signatures of BAT and WAT that may allow differentiation on MR imaging. Copyright © 2011 Wiley-Liss, Inc.
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              Using adiabatic inversion pulses for long-T2 suppression in ultrashort echo time (UTE) imaging.

              Ultrashort echo time (UTE) imaging is a technique that can visualize tissues with sub-millisecond T(2) values that have little or no signal in conventional MRI techniques. The short-T(2) tissues, which include tendons, menisci, calcifications, and cortical bone, are often obscured by long-T(2) tissues. This paper introduces a new method of long-T(2) component suppression based on adiabatic inversion pulses that significantly improves the contrast of short-T(2) tissues. Narrow bandwidth inversion pulses are used to selectively invert only long-T(2) components. These components are then suppressed by combining images prepared with and without inversion pulses. Fat suppression can be incorporated by combining images with the pulses applied on the fat and water resonances. Scaling factors must be used in the combination to compensate for relaxation during the preparation pulses. The suppression is insensitive to RF inhomogeneities because it uses adiabatic inversion pulses. Simulations and phantom experiments demonstrate the adiabatic pulse contrast and how the scaling factors are chosen. In vivo 2D UTE images in the ankle and lower leg show excellent, robust long-T(2) suppression for visualization of cortical bone and tendons. Copyright 2007 Wiley-Liss, Inc.
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                Author and article information

                Journal
                Magnetic Resonance in Medicine
                Magn. Reson. Med.
                Wiley
                07403194
                August 2016
                August 2016
                August 26 2015
                : 76
                : 2
                : 577-582
                Affiliations
                [1 ]GE Healthcare, University of California; San Diego California USA
                [2 ]Radiology Department; University of California; San Diego California USA.
                Article
                10.1002/mrm.25823
                4769116
                26309221
                31e207f6-ff5d-44de-8bd5-97afdb541ae3
                © 2015

                http://doi.wiley.com/10.1002/tdm_license_1.1

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