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      The magnitude and predictors of self-medication amongst street dwellers in Ethiopia: a multicentre study

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          Abstract

          Background

          Low levels of living standards amongst street dwellers worldwide limit their access to conventional healthcare services, resulting in self-medication use for the treatment of an illness. Nevertheless, self-medication use has risks, including adverse drug reactions, increased polypharmacy, drug resistance, drug dependence, drug interactions and incorrect diagnosis. Ethiopia has a large street-dwelling community; however, there are no studies conducted in Ethiopia assessing self-medication use amongst street dwellers. This study provides insight into self-medication use and predictors amongst street dwellers in Ethiopia.

          Methods

          A community-based, multicentre cross- sectional study was conducted amongst street dwellers from 1 September 2022 to 1 February 2023 at community drug-retail outlets in the three major cities in the Amhara region of Ethiopia. The data were obtained using an interviewer-administered questionnaire. Frequencies and percentages of descriptive statistics were calculated. Bivariable and multivariable logistic regression analyses were employed to indicate predictors of self-medication use. To determine statistical significance, a 95% confidence interval with a p value below 0.05 was utilized.

          Results

          The prevalence of self-medication use was 67.4%. Time and financial savings were reported as the reasons for most self-medication use. The most commonly reported illnesses for which people sought self-medication were gastrointestinal diseases. Low monthly income (adjusted OR 3.72, 95% CI 2.34–5.91) and residing near sewage areas (adjusted OR 3.37, 95% CI 2.03–5.58) were significantly associated with self-medication use.

          Conclusion

          Street dwellers had a high rate of self- medication use. Residing near sewage areas and having a low level of income were factors in self-medication use. Gastrointestinal diseases, respiratory ailments and dermatological conditions were the most frequently reported complaints, whereas antimicrobials and anthelmintics were the most commonly used medications. We recommend that healthcare services enhance outreach programmes to the most vulnerable people, such as street dwellers, especially those with lower monthly incomes and who live near sewage areas, to reduce self-medication rates.

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          Most cited references53

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          How urbanization affects the epidemiology of emerging infectious diseases

          The world is becoming more urban every day, and the process has been ongoing since the industrial revolution in the 18th century. The United Nations now estimates that 3.9 billion people live in urban centres. The rapid influx of residents is however not universal and the developed countries are already urban, but the big rise in urban population in the next 30 years is expected to be in Asia and Africa. Urbanization leads to many challenges for global health and the epidemiology of infectious diseases. New megacities can be incubators for new epidemics, and zoonotic diseases can spread in a more rapid manner and become worldwide threats. Adequate city planning and surveillance can be powerful tools to improve the global health and decrease the burden of communicable diseases.
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            Self-medication and antibiotic resistance: Crisis, current challenges, and prevention

            The present study aims to explore the crisis of antibiotic resistance and discover more about the current challenges related to self-medication. The current challenges related to antibiotic resistance are unique and differ from the challenges of the past since new bacterial pathogens are involved and continue to evolve. Strains with resistance to multiple antibiotic classes have emerged which the discovery of new antibiotics has failed to match. The consequences of antibiotic resistance are grave with mortality and morbidity continually on the rise. This paper also highlights the possible interventions that can be effective at the micro or individual level in the prevention of development of antibiotic resistance.
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              Antibiotic knowledge and self-medication practices in a developing country: A cross-sectional study.

              Self-medication is identified by the World Health Organization as a major factor leading to antibiotics overuse, misuse and resistance. This study's objectives were to evaluate the knowledge and self-medication with antibiotics in a sample of the population of Lebanon.
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                Author and article information

                Contributors
                Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole: Project administrationRole: SupervisionRole: Writing – original draftRole: Writing – review & editingRole: ResourcesRole: SoftwareRole: Visualization
                Role: Data curationRole: InvestigationRole: SupervisionRole: SoftwareRole: Visualization
                Role: ConceptualizationRole: InvestigationRole: ResourcesRole: SoftwareRole: Visualization
                Role: Data curationRole: MethodologyRole: Project administrationRole: Writing – original draftRole: SoftwareRole: Visualization
                Role: Formal analysisRole: Project administrationRole: Writing – original draftRole: Writing – review & editingRole: SoftwareRole: Visualization
                Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: SupervisionRole: Writing – review & editingRole: ResourcesRole: SoftwareRole: Visualization
                Journal
                Drugs Context
                Drugs Context
                DIC
                Drugs in Context
                BioExcel Publishing Ltd
                1745-1981
                1740-4398
                2024
                11 January 2024
                : 13
                : 2023-7-2
                Affiliations
                [1 ]Department of Pharmacy, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia
                [2 ]Department of Pharmacy, College of Medicine and Health Sciences, Bahr Dar University, Bahr Dar, Ethiopia
                [3 ]Department of Pharmacy, College of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
                [4 ]Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
                Author notes
                Correspondence: Rahel Belete Abebe, Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia, PO Box: 196. Email: rahelbelete32@ 123456gmail.com
                Author information
                https://orcid.org/0000-0003-3528-0703
                https://orcid.org/0000-0002-0201-6829
                https://orcid.org/0000-0003-2673-7409
                https://orcid.org/0000-0002-1540-3369
                https://orcid.org/0000-0002-2560-2951
                Article
                dic-2023-7-2
                10.7573/dic.2023-7-2
                10803126
                2f2e9239-f43e-4a52-89a0-61a4fb42dfd4
                Copyright © 2024 Zeleke TK, Alamirew BD, Bazezew ZA, Alemu MA, Jara AG, Abebe RB

                Published by Drugs in Context under Creative Commons License Deed CC BY NC ND 4.0, which allows anyone to copy, distribute, and transmit the article provided it is properly attributed in the manner specified below. No commercial use without permission.

                History
                : 01 September 2023
                : 29 November 2023
                Categories
                Original Research

                ethiopia,self-medication,street dwellers
                ethiopia, self-medication, street dwellers

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