Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Baccelli, Irène; Gareau, Yves; Lehnertz, Bernhard; Gingras, Stephane; Spinella, Jean-François; Corneau, Sophie; Mayotte, Nadine; Girard, Simon Louis; Fréchette, Mélanie; Blouin-Chagnon, Valérie; Leveille, Koryne; Boivin, Isabel; MacRae, Tara; Krosl, Jana; Thiollier, Clarisse; Lavallée, Vincent-Philippe; Kanshin, Evgeny; Bertomeu, Thierry; Coulombe-Huntington, Jasmin; St-Denis, Corinne; Bordeleau, Marie-Eve; Boucher, Genevieve; Roux, Philippe P.; Lemieux, Sébastien; Tyers, Mike; Thibault, Pierre; Hébert, Josée; Marinier, Anne; Sauvageau, Guy

doi:10.1016/j.ccell.2019.06.003

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Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Author(s): Irène Baccelli , Yves Gareau , Bernhard Lehnertz , Stéphane Gingras , Jean-François Spinella , Sophie Corneau , Nadine Mayotte , Simon Girard , Mélanie Frechette , Valérie Blouin-Chagnon , Koryne Leveillé , Isabel Boivin , Tara MacRae , Jana Krosl , Clarisse Thiollier , Vincent-Philippe Lavallée , Evgeny Kanshin , Thierry Bertomeu , Jasmin Coulombe-Huntington , Corinne St-Denis , Marie-Eve Bordeleau , Geneviève Boucher , Philippe P. Roux , Sébastien Lemieux , Mike Tyers , Pierre Thibault , Josée Hébert , Anne Marinier , Guy Sauvageau

Publication date Created: July 2019

Publication date (Print): July 2019

Journal: Cancer Cell

Publisher: Elsevier BV

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Journal

Title: Cancer Cell

Abbreviated Title: Cancer Cell

Publisher: Elsevier BV

ISSN (Print): 15356108

Publication date Created: July 2019

Publication date (Print): July 2019

Volume: 36

Issue: 1

Pages: 84-99.e8

Article

DOI: 10.1016/j.ccell.2019.06.003

PubMed ID: 31287994

SO-VID: 2d888158-8b79-4d3e-b831-e7cb2f56277e

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https://www.elsevier.com/tdm/userlicense/1.0/

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