Reaction times (RTs) slow and become more variable with age. Research samples are typically small, biased, and of restricted age range. Consequently, little is known about the precise pattern of change, whereas evidence for sex differences is equivocal. The authors reanalyzed data for 7,130 adult participants in the United Kingdom Health and Lifestyle Survey, originally reported by F. A. Huppert (1987). The authors modeled the age differences in simple and 4-choice reaction time means and variabilities and tested for sex differences. Simple RT shows little slowing until around 50, whereas choice RT slows throughout the adult age range. The aging of choice RT variability is a function of its mean and the error rate. There are significant sex differences, most notably for choice RT variability. ((c) 2006 APA, all rights reserved).