TAS2R38 and CA6 genetic polymorphisms, frequency of bitter food intake, and blood biomarkers among elderly woman.

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Abstract

Taste sensitivity is one of the most important biological determinants of food choice. Three SNPs of the TAS2R38 gene (rs713598, rs1726866, and rs10246939) give rise to two common haplotypes: PAV and AVI. These haplotypes, as well as an SNP within the CA6 gene (rs2274333) that encodes carbonic anhydrase VI (CA6), correlate with bitterness perception. The extent of consumption of bitter food may influence some health outcomes. The aim of this study is thus to investigate the impact of the TAS2R38 and CA6 genetic polymorphisms on the choice of bitter food, BMI, blood lipoprotein, and glucose concentrations as well as systemic inflammation in elderly women.

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Journal

Journal ID (iso-abbrev): Appetite

Title: Appetite

Publisher: Elsevier BV

ISSN (Electronic): 1095-8304

ISSN (Print): 0195-6663

Publication date (Electronic): September 01 2017

Volume: 116

Affiliations

[1 ] Molecular Metabolism Laboratory, Department of Human Nutrition and Hygiene, Faculty of Food Sciences, Poznan University of Life Sciences, Wojska Polskiego 31, 60-624 Poznan, Poland. Electronic address: joanstec@up.poznan.pl.

[2 ] Molecular Metabolism Laboratory, Department of Human Nutrition and Hygiene, Faculty of Food Sciences, Poznan University of Life Sciences, Wojska Polskiego 31, 60-624 Poznan, Poland.

Article

Publisher Item ID: S0195-6663(16)30736-X

DOI: 10.1016/j.appet.2017.04.029

PubMed ID: 28455260

SO-VID: 2d02df03-26e2-431f-9b54-d2d08957376f

History

Keywords: TAS2R38,Genetic polymorphism,Frequency of eating,CA6,Bitter taste

Data availability:

Keywords: TAS2R38, Genetic polymorphism, Frequency of eating, CA6, Bitter taste

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