39
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Nódulo pulmonar solitario de localización subpelural: aspectos clínicos, radiológicos, histopatológico y diagnósticos diferenciales, a propósito de un caso clínico Translated title: Pulmonary solitary nodule of subpelural localization: clinical, radiological, histopathological and differential diagnoses, regarding a clinical case

      case-report

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Fundamento: el cáncer de pulmón es la causa más frecuente de mortalidad en el mundo. Es uno de los cánceres con peor pronóstico, suele diagnosticarse en estadios avanzados. La detección precoz, en la fase de nódulo pulmonar, permitiría una intervención terapéutica más temprana, al mejorar el pronóstico y la supervivencia. Los diagnósticos más importantes son: la radiografía de tórax, tomografía computarizada, punción aspirativa con aguja fina, existe una gran cantidad de diagnósticos diferenciales que incluyen lesiones benignas y malignas. Objetivo: describir los aspectos clínicos, radiológicos, histopatológico y diagnósticos diferenciales del nódulo pulmonar solitario de localización subpleural. Caso clínico: se describe un caso clínico con un nódulo pulmonar solitario y diagnóstico presuntivo inicial de carcinoma pulmonar; tras ser estudiado y realizarle lobectomía pulmonar; el diagnóstico como causa inflamatoria fue una neumonía. Conclusiones: el mayor por ciento de los nódulos pulmonares solitarios son neoplasias secundarias a afecciones con las que se puede establecer el diagnóstico diferencial. La causa más frecuente son los granulomas secundarios a afecciones inflamatorias infecciosas, al seguir en orden de frecuencia el cáncer y dentro de ellos el carcinoma broncógeno.

          Translated abstract

          Background: lung cancer is the most common cause of cancer mortality worldwide. It is one of the cancers with worse prognosis, since it is usually diagnosed in advanced stages. Early detection, in the pulmonary nodule phase, would allow an earlier therapeutic intervention, improving prognosis and survival. Important diagnostic tools include chest radiography, computed tomography, fine needle aspiration, and a large number of differential diagnoses including benign and malignant lesions. Objective: to describe the clinical, radiological, histopathological and differential diagnoses of the solitary pulmonary nodule of subpleural location. Clinical case: a clinical case with a solitary pulmonary nodule and initial presumptive diagnosis of lung carcinoma is described; after being studied and performed lung lobectomy, diagnosed as an inflammatory cause, pneumonia. Conclusions: 95 % of solitary pulmonary nodules are neoplasias secondary to conditions with which a differential diagnosis can be established. The most frequent cause is granulomas secondary to infectious inflammatory conditions, following in order of frequency the cancer and within them the bronchogenic carcinoma.

          Related collections

          Most cited references11

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Assessment of the cancer risk factors of solitary pulmonary nodules

          There are no large samples or exact prediction models for assessing the cancer risk factors of solitary pulmonary nodules (SPNs) in the Chinese population. We retrospectively analyzed the clinical and imaging data of patients with SPNs who underwent computer tomography guided needle biopsy in our hospital from Jan 1st of 2011 to March 30th of 2016. These patients were divided into a development data set and a validation data set. These groups included 1078 and 344 patients, respectively. A prediction model was developed from the development data set and was validated with the validation data set using logistic regression. The predictors of cancer in our model included female gender, age, pack-years of smoking, a previous history of malignancy, nodule size, lobulated and spiculated edges, lobulation alone and spiculation alone. The Area Under the Curves, sensitivity and specificity of our model in the development and validation data sets were significantly higher than those of the Mayo model and VA model (p 8 mm in size. SPNs in female patients, as well as SPNs featuring a combination of lobulated and spiculated edges or lobulated edges alone, should be evaluated carefully due to the probability that they are malignant.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            PET scanning and the solitary pulmonary nodule.

            The finding of a solitary pulmonary nodule on a chest radiograph is a common problem in pulmonary medicine and is seen in about 1 in 500 chest radiographs. Of the benign lesions, 80% are infectious granulomas, 10% are hamartomas, and the remaining 10% are caused by a variety of rarer disorders including noninfectious granulomas and other benign tumors. The prevalence of malignancy ranges from 10% to 68% in the literature. Because of the high prevalence of malignancy and the poor survival for lung cancer, early detection, characterization, and directed treatment are important. Positron emission tomography with 18-Fluorodeoxyglucose (FDG-PET) can play an important role in the evaluation and management of solitary pulmonary nodules. This includes improved characterization of solitary pulmonary nodules with very high negative predictive value and improved staging information when performed in association with CT, especially for nodal staging and identification of unsuspected stage IV disease. PET also provides additional information for management of solitary pulmonary nodules by estimating the probability of malignancy.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Radiologic evaluation of the solitary pulmonary nodule.

              The radiologic evaluation of solitary pulmonary nodules can be a complex process. Modalities, which can be used, include the chest radiograph, computed tomography, and positron emission tomography scanning. Interventional radiology can also play a role with image-guided transthoracic needle aspiration of indeterminate pulmonary nodules. The primary role of radiologic evaluation is to try to differentiate benign from malignant pulmonary nodules. The imaging findings that can be helpful in making this distinction as well as the limitations of each of the modalities are discussed. For the purpose of this review, solitary pulmonary nodule mimics such as skin or rib lesions, vascular malformations, and areas of rounded atelectasis are not discussed. Copyright 2002, Elsevier Science (USA). All rights reserved.
                Bookmark

                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Journal
                amc
                Revista Archivo Médico de Camagüey
                AMC
                Editorial Ciencias Médicas Camagüey (Camagüey, , Cuba )
                1025-0255
                October 2017
                : 646-651
                Affiliations
                [01] Santa Cruz de Tenerife orgnameCentro de Salud de El Paso España
                [02] Santa Cruz de Tenerife orgnameUniversidad de La Laguna orgdiv1Facultad de Medicina España
                Article
                S1025-02552017000500011
                2b98da6f-f1e8-43b1-89d3-d4fa1b8a7fa5

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 13 June 2017
                : 21 January 2017
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 12, Pages: 6
                Product

                SciELO Cuba


                PNEUMONIA,NEOPLASIAS PULMONARES,NÓDULO PULMONAR SOLITARIO,CASE REPORTS,MIDDLE AGED,LUNG NEOPLASMS,SOLITARY PULMONARY NODULE,INFORMES DE CASOS,MEDIANA EDAD,NEUMONÍA

                Comments

                Comment on this article