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      Uncovering the knowledge gaps: A survey on human monkeypox infection among men who have sex with men in Nepal

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          Abstract

          The monkeypox virus (MPOX) poses a major threat to the health of people, particularly among men who have sex with men (MSM). However, the knowledge regarding MPOX among MSM in Nepal is poorly understood. Therefore, the present study aimed to assess the knowledge of human monkeypox among Nepalese MSM. A cross-sectional face-to-face survey was conducted among purposively selected 250 participants (mean age 27.6 ± 8.9 years) in Nepal between October and December 2022. The questionnaire consisted of informed consent along with questions covering age, education, and MPOX. The findings demonstrated that the majority of MSM in Nepal had poor knowledge of MPOX. Around 87% of participants had no idea whether MPOX is contagious or not. However, the results call for immediate action to improve knowledge of MSM through health education programs and appropriate interventions to spread awareness of MPOX.

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          There is need for improving knowledge of MSM through health education programs and appropriate interventions to spread awareness of MPOX.

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          Most cited references16

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          Digital technologies in the public-health response to COVID-19

          Digital technologies are being harnessed to support the public-health response to COVID-19 worldwide, including population surveillance, case identification, contact tracing and evaluation of interventions on the basis of mobility data and communication with the public. These rapid responses leverage billions of mobile phones, large online datasets, connected devices, relatively low-cost computing resources and advances in machine learning and natural language processing. This Review aims to capture the breadth of digital innovations for the public-health response to COVID-19 worldwide and their limitations, and barriers to their implementation, including legal, ethical and privacy barriers, as well as organizational and workforce barriers. The future of public health is likely to become increasingly digital, and we review the need for the alignment of international strategies for the regulation, evaluation and use of digital technologies to strengthen pandemic management, and future preparedness for COVID-19 and other infectious diseases.
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            Human monkeypox.

            Human monkeypox is a zoonotic Orthopoxvirus with a presentation similar to smallpox. Clinical differentiation of the disease from smallpox and varicella is difficult. Laboratory diagnostics are principal components to identification and surveillance of disease, and new tests are needed for a more precise and rapid diagnosis. The majority of human infections occur in Central Africa, where surveillance in rural areas with poor infrastructure is difficult but can be accomplished with evidence-guided tools and educational materials to inform public health workers of important principles. Contemporary epidemiological studies are needed now that populations do not receive routine smallpox vaccination. New therapeutics and vaccines offer hope for the treatment and prevention of monkeypox; however, more research must be done before they are ready to be deployed in an endemic setting. There is a need for more research in the epidemiology, ecology, and biology of the virus in endemic areas to better understand and prevent human infections.
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              Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia

              Introduction: Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population in Indonesia. Methods: A cross-sectional online survey was conducted between March 25 and April 6, 2020. Participants were asked if they would accept a free vaccine which was 95 or 50% effective. Using a logistic regression model, we assessed the associations between sociodemographic characteristics, exposure to COVID-19 information, or perceived risk of infection with acceptance of a hypothetical COVID-19 vaccine. Results: Among 1,359 respondents, 93.3% of respondents (1,268/1,359) would like to be vaccinated for a 95% effective vaccine, but this acceptance decreased to 67.0% (911/1,359) for a vaccine with 50% effectiveness. For a 95% effective vaccine, being a healthcare worker and having a higher perceived risk of COVID-19 infection were associated with higher acceptance, adjusted odds ratio (aOR): 2.01; 95%CI: 1.01, 4.00 and aOR: 2.21; 95%CI: 1.07, 4.59, respectively; compared to civil servants, being retired was associated with less acceptance (aOR: 0.15; 95%CI: 0.04, 0.63). For a 50% effective vaccine, being a healthcare worker was also associated with greater acceptance, aOR: 1.57; 95%CI: 1.12, 2.20. Conclusion: Acceptance of a COVID-19 vaccine was highly influenced by the baseline effectiveness of the vaccine. Preparing the general population to accept a vaccine with relatively low effectiveness may be difficult.
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                Author and article information

                Journal
                9918697572306676
                52945
                Health Prospect
                Health Prospect
                Health prospect : journal of public health
                2091-2021
                2091-203X
                5 November 2023
                2 November 2023
                10 November 2023
                : 22
                : 1
                : 1-6
                Affiliations
                [1 ]Nepal Health Frontiers, Tokha-5, Kathmandu, Nepal
                [2 ]University of Connecticut, Department of Allied Health Sciences, Storrs, CT 06269, USA
                [3 ]Yale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, 135 College St.,Suite 323, New Haven, CT 06510, USA
                [4 ]Blue Diamond Society, Kathmandu, Nepal
                Author notes

                Author Contributions

                RS conceptualized and conducted the research. RS and KP performed the statistical analysis. KP prepared the first draft of the manuscript by taking the subsequent help of RS, and KG. All authors critically reviewed the manuscript and provided insightful input. RS supervised the study. All authors read, reviewed, and agreed to the last version of the manuscript.

                [* ] Corresponding author: Roman Shrestha, Ph.D., MPH, roman.shrestha@ 123456uconn.edu
                Article
                NIHMS1942297
                10.3126/hprospect.v22i1.53504
                10636784
                37954124
                2b708997-3654-4ec0-a4ae-6a730776067c

                This is an open access article distributed on the terms of Creative Commons Attribution3.0 license. This work may be freely reproduced, distributed, transmitted, modified, or otherwise used provided that the original work is properly cited. Author emails are available at the end of the article.

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                Article

                monkeypox,mpox,men who have sex with men,msm,nepal
                monkeypox, mpox, men who have sex with men, msm, nepal

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