15
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Autoenxerto de crista ilíaca de coelhos na união vertebral dorsolateral lombar Translated title: Iliac crest autograft in rabbit dorsolateral spinal fusion

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Foi realizada artrodese dorsolateral das vértebras lombares L5-L6 de coelhos, avaliando-se a eficácia do autoenxerto da crista ilíaca na promoção de união vertebral. Foram utilizados 33 coelhos da raça Nova Zelândia Branco, distribuídos em dois grupos, com nove indivíduos no grupo 1 (G1), submetidos a descorticação bilateral dos processos transversos; e vinte e quatro indivíduos no grupo 2 (G2), que receberam 2g de autoenxerto da crista ilíaca sobre a área de descorticação. Três coelhos do G1 e oito do G2 foram submetidos à eutanásia as cinco, sete e nove semanas após o ato operatório e à avaliações por palpação, radiográfica e histológica no local do procedimento. Testes biomecânicos para avaliação de força e rigidez da união foram realizados somente nos animais do G2 e as vértebras adjacentes não operadas, serviram de controle. Os animais do G1 apresentaram mobilidade normal à palpação do segmento operado em todos os momentos de avaliação e não apresentaram evidência radiográfica de união. Na avaliação histológica foi observada discreta reação periosteal, sem evidências de formação de ponte óssea. No G2, as avaliações por palpação e radiográficas evidenciaram indícios de união óssea as cinco semanas, intensificando-se ao longo das semanas de avaliação. Na análise histológica foi observada reabsorção de fragmentos ósseos as cinco semanas, predominância de trabéculas ósseas e corações condróides, além de suprimento sanguíneo abundante as sete semanas e osteointegração em todo leito de enxertia as nove semanas, com predomínio de formação óssea endocondral. Os testes biomecânicos evidenciaram aumento da força e rigidez da massa óssea ao longo do tempo de avaliação. Quando foi realizada comparação das vértebras tratadas e não tratadas, os índices de união foram maiores em todos os momentos, no grupo tratado. Com os resultados foi possível concluir que alta percentagem de união vertebral foi conseguida quando o osso autógeno da crista ilíaca foi utilizado como material de enxertia em coelhos.

          Translated abstract

          The effectiveness of the iliac crest autograft in dorsolateral spinal fusion promotion of the lumbar vertebral body L5-L6 was evaluated in 33 New Zealand White rabbits, distributed in two groups, with nine animals in group 1 (G1), submitted the bilateral transverse processes decortification; and twenty-four in group 2 (G2), which received 2g of iliac crest autograft on decortificed bilateral transverse processes. Three rabbits of G1 and eight of G2 were killed at 5, 7 and 9 weeks after surgery and submitted to palpation, X-ray and light microscopic evaluations. The fusion site of animals of G2 was submitted to biomechanic tests accomplished for evaluation of force and rigidity. All animals of G1 presented normal mobility of the segment operated in all moments of evaluation and they didn't present fusion evidence in X-ray analysis. In the light microscopic evaluations periosteal discreet reaction was observed, without evidence of bony bridge formation. In G2, evaluation for palpation and x-rays evidenced bone fusion to the 5 weeks, intensifying along the weeks. At 5 weeks, in the light microscopic analysis, reabsorption of bone fragments was observed, presence of trabecular bone and chondroides hearts, besides the abundant irrigation to the 7 weeks and osteointegration in every grafted bed to the 9 weeks, with bone endochondral formation prevailing. Force and rigidity increase of the fusion bone mass along the time of evaluation was observed in the biomechanic test.. When a comparison of the treated vertebrae and no treated was accomplished, the union indexes were larger in all of the moments, in the treated group. A high percentage of vertebral fusion was gotten when iliac crest autograft was used in rabbits.

          Related collections

          Most cited references15

          • Record: found
          • Abstract: found
          • Article: not found

          Results of lumbosacral fusion for degenerative disc disease with and without instrumentation. Two- to five-year follow-up.

          Functional and surgical outcomes are reported in two consecutive groups of patients who underwent one- and two-level lumbosacral fusion. The first group underwent standard posterolateral lumbosacral fusion, and the second group underwent lumbosacral fusion with compression U-rod instrumentation. Fusions were carried out over all painful, abnormal levels documented by discography. the pseudarthrosis rate without instrumentation was 35%, in contrast to 6% with instrumentation. In both groups of patients with chronic low-back pain secondary to degenerative disc disease, solid lumbosacral fusion was associated with decreased pain and higher return to work rates. Poorest results were associated with prolonged periods of preoperative disability and long-term disability claims.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Experience in posterior lumbar interbody fusion: unicortical versus bicortical autologous grafts

              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Postoperative spine infections

                Bookmark

                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                bjvras
                Brazilian Journal of Veterinary Research and Animal Science
                Braz. J. Vet. Res. Anim. Sci.
                Faculdade de Medicina Veterinária e Zootecnia / Universidade de São Paulo (São Paulo )
                1678-4456
                August 2004
                : 41
                : 4
                : 254-260
                Affiliations
                [1 ] Universidade Federal de Viçosa Brazil
                Article
                S1413-95962004000400006
                10.1590/S1413-95962004000400006
                2aeecf67-4ae4-4052-9a0c-69afae863d2a

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=1413-9596&lng=en
                Categories
                AGRICULTURE, DAIRY & ANIMAL SCIENCE
                VETERINARY SCIENCES

                Animal agriculture,General veterinary medicine
                Bone graft,Arthrodesis,Lombar spine,Enxerto ósseo,Artrodese,Coluna vertebral

                Comments

                Comment on this article