Riho Tateyama-Makino:
ORCID: https://orcid.org/0000-0001-5206-8339
Role: Formal analysisRole: InvestigationRole: MethodologyRole: ValidationRole: VisualizationRole:
Writing – original draft
Mari Abe-Yutori: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ValidationRole: VisualizationRole:
Writing – original draft
Taku Iwamoto: Role: ConceptualizationRole: MethodologyRole: VisualizationRole: Writing – original
draft
Kota Tsutsumi:
ORCID: https://orcid.org/0000-0003-1371-2915
Role: ConceptualizationRole: MethodologyRole: VisualizationRole: Writing – original
draft
Motonori Tsuji:
ORCID: https://orcid.org/0000-0003-0734-0334
Role: InvestigationRole: MethodologyRole: SoftwareRole: ValidationRole: VisualizationRole:
Writing – original draft
Satoru Morishita: Role: ConceptualizationRole: Writing – review & editing
Kei Kurita: Role: ConceptualizationRole: Writing – review & editing
Yukio Yamamoto: Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
Writing – review & editing
Eiji Nishinaga: Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
Writing – review & editing
Keiichi Tsukinoki: Role: ConceptualizationRole: SupervisionRole: Writing – review & editing
Etsuro Ito: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
17
September
2021
Publication date Collection: 2021
Publication date PMC-release: 17
September
2021
Volume: 16
Issue: 9
Electronic Location Identifier: e0257705
Affiliations
[1
]
Research & Development Headquarters, Lion Corporation, Edogawa-ku, Tokyo, Japan
[2
]
Institute of Molecular Function, Misato-shi, Saitama, Japan
[3
]
Division of Environmental Pathology, Department of Oral Science, Kanagawa Dental University,
Yokosuka, Kanagawa, Japan
Waseda University: Waseda Daigaku, JAPAN
Author notes
Competing Interests: We have read the journal‘s policy and the authors of this manuscript have the following
competing interests: R Tateyama-Makino, M Abe-Yutori, T Iwamoto, K Tsutsumi, S Morishita,
K Kurita, Y Yamamoto, and E Nishinaga are employees of the Lion Corporation (Tokyo,
Japan). M Tsuji is a President of the Institute of Molecular Function (Saitama, Japan).
Molecular docking simulation was performed by the Institute of Molecular Function
under a consignment from the Lion Corporation. K Tsukinoki has received fees for technical
guidance from the Lion Corporation. This does not alter our adherence to PLOS ONE
policies on sharing data and materials.
‡ These authors have contributed equally to this work and share first authorship
Author information
Article
Publisher ID:
PONE-D-21-20049
DOI: 10.1371/journal.pone.0257705
PMC ID: 8448299
PubMed ID: 34534255
SO-VID: 2a2e47c5-d537-4e15-b25e-0c0e1c43e2b5
Copyright © © 2021 Tateyama-Makino et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
Lion Corporation
This work was fully funded by Lion Corporation (
https://www.lion.co.jp/en/). R Tateyama-Makino, M Abe-Yutori, T Iwamoto, K Tsutsumi, S Morishita, K Kurita,
Y Yamamoto, and E Nishinaga are employees of Lion Corporation. The Lion Corporation
provided support in the form of salaries for authors R Tateyama-Makino, M Abe-Yutori,
T Iwamoto, K Tsutsumi, S Morishita, K Kurita, Y Yamamoto, and E Nishinaga. M Tsuji
is a President of the Institute of Molecular Function (Saitama, Japan). Molecular
docking simulation was performed by the Institute of Molecular Function under a consignment from
the Lion Corporation. K Tsukinoki has received fees for technical guidance from the
Lion Corporation. The funders had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript. The specific roles of these
authors are articulated in the “author contributions” section.
Subject:
Research Article
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Biology and life sciences
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Organisms
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Viruses
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RNA viruses
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Biology and life sciences
Subject:
Microbiology
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Medical microbiology
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Microbial pathogens
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Viral pathogens
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Medicine and health sciences
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Pathology and laboratory medicine
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Pathogens
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Microbial pathogens
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Viral pathogens
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Biology and life sciences
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Organisms
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Viruses
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Viral pathogens
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Coronaviruses
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SARS coronavirus
Subject:
SARS CoV 2
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Physical Sciences
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Physics
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Condensed Matter Physics
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Solid State Physics
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Crystallography
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Crystal Structure
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Biology and Life Sciences
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Biochemistry
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Proteins
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Protein Interactions
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Biology and Life Sciences
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Biochemistry
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Enzymology
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Enzymes
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Proteases
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Serine Proteases
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Biology and Life Sciences
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Biochemistry
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Proteins
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Enzymes
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Proteases
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Serine Proteases
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Physical Sciences
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Materials Science
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Materials
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Surfactants
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Biology and Life Sciences
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Biochemistry
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Biochemical Simulations
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Biology and Life Sciences
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Computational Biology
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Biochemical Simulations
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Medicine and Health Sciences
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Diagnostic Medicine
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Virus Testing
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Biology and Life Sciences
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Anatomy
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Body Fluids
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Saliva
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Medicine and Health Sciences
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Body Fluids
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Biology and Life Sciences
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