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TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.
Pin-Yu Perera, Jace W. Jones, Mildred M Cody, Jennifer Major, Jason G. Williams, Nicole N Vogel, Vladimir Toshchakov, B. Hamilton, Robert J. Fenton, SHULING ZHANG, Karen Thomas
2002-03-31
Adaptor Proteins, Signal Transducing, Animals, Antigens, Differentiation, genetics, metabolism, Cell Line, Chemokine CXCL10, Chemokines, CXC, DNA-Binding Proteins, Drosophila Proteins, Enzyme Activation, Escherichia coli, Female, Gene Expression, drug effects, Interferon-Stimulated Gene Factor 3, Interferon-beta, Interleukin-1, Lipopolysaccharides, pharmacology, Macrophages, cytology, Male, Membrane Glycoproteins, agonists, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Monocyte Chemoattractant Proteins, Myeloid Differentiation Factor 88, Nitric Oxide Synthase, Nitric Oxide Synthase Type II, Phosphorylation, RNA, Messenger, Receptors, Cell Surface, Receptors, Immunologic, Receptors, Interleukin-1, STAT1 Transcription Factor, Signal Transduction, Toll-Like Receptor 2, Toll-Like Receptor 4, Toll-Like Receptors, Trans-Activators, Transcription Factors, Tumor Necrosis Factor-alpha
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Adaptor Proteins, Signal Transducing,Animals,Antigens, Differentiation,genetics,metabolism,Cell Line,Chemokine CXCL10,Chemokines, CXC,DNA-Binding Proteins,Drosophila Proteins,Enzyme Activation,Escherichia coli,Female,Gene Expression,drug effects,Interferon-Stimulated Gene Factor 3,Interferon-beta,Interleukin-1,Lipopolysaccharides,pharmacology,Macrophages,cytology,Male,Membrane Glycoproteins,agonists,Mice,Mice, Inbred C3H,Mice, Inbred C57BL,Mice, Knockout,Mitogen-Activated Protein Kinases,Monocyte Chemoattractant Proteins,Myeloid Differentiation Factor 88,Nitric Oxide Synthase,Nitric Oxide Synthase Type II,Phosphorylation,RNA, Messenger,Receptors, Cell Surface,Receptors, Immunologic,Receptors, Interleukin-1,STAT1 Transcription Factor,Signal Transduction,Toll-Like Receptor 2,Toll-Like Receptor 4,Toll-Like Receptors,Trans-Activators,Transcription Factors,Tumor Necrosis Factor-alpha
Adaptor Proteins, Signal Transducing, Animals, Antigens, Differentiation, genetics, metabolism, Cell Line, Chemokine CXCL10, Chemokines, CXC, DNA-Binding Proteins, Drosophila Proteins, Enzyme Activation, Escherichia coli, Female, Gene Expression, drug effects, Interferon-Stimulated Gene Factor 3, Interferon-beta, Interleukin-1, Lipopolysaccharides, pharmacology, Macrophages, cytology, Male, Membrane Glycoproteins, agonists, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Monocyte Chemoattractant Proteins, Myeloid Differentiation Factor 88, Nitric Oxide Synthase, Nitric Oxide Synthase Type II, Phosphorylation, RNA, Messenger, Receptors, Cell Surface, Receptors, Immunologic, Receptors, Interleukin-1, STAT1 Transcription Factor, Signal Transduction, Toll-Like Receptor 2, Toll-Like Receptor 4, Toll-Like Receptors, Trans-Activators, Transcription Factors, Tumor Necrosis Factor-alpha