Quantification of coronary flow reserve in patients with ischaemic and non-ischaemic cardiomyopathy and its association with clinical outcomes.

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Abstract

Patients with left ventricular systolic dysfunction frequently show abnormal coronary vascular function, even in the absence of overt coronary artery disease. Moreover, the severity of vascular dysfunction might be related to the aetiology of cardiomyopathy.We sought to determine the incremental value of assessing coronary vascular dysfunction among patients with ischaemic (ICM) and non-ischaemic (NICM) cardiomyopathy at risk for adverse cardiovascular outcomes.

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Author and article information

Journal

Journal ID (iso-abbrev): Eur Heart J Cardiovasc Imaging

Title: European heart journal cardiovascular Imaging

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 2047-2412

ISSN (Print): 2047-2404

Publication date (Electronic): Aug 2015

Volume: 16

Issue: 8

Affiliations

[1 ] Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, ASB-L1 037C, Boston, MA 02115, USA Non-Invasive Cardiovascular Imaging Program, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA Non-Invasive Cardiovascular Imaging Program, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.

[2 ] Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA Divisions of Nuclear Medicine and Cardiothoracic Imaging, Department of Radiology, University of Michigan, Ann Arbor, MI, USA.

[3 ] Non-Invasive Cardiovascular Imaging Program, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA Non-Invasive Cardiovascular Imaging Program, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.

[4 ] Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.

[5 ] Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, ASB-L1 037C, Boston, MA 02115, USA.

[6 ] Non-Invasive Cardiovascular Imaging Program, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA Non-Invasive Cardiovascular Imaging Program, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.

[7 ] Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, ASB-L1 037C, Boston, MA 02115, USA Non-Invasive Cardiovascular Imaging Program, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA Non-Invasive Cardiovascular Imaging Program, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA mdicarli@partners.org.

Article

Publisher Item ID: jev012

DOI: 10.1093/ehjci/jev012

PMC ID: 4592320

PubMed ID: 25719181

SO-VID: 290dfd1b-0ef5-423a-bfa8-e96f0f87d092

History

Keywords: myocardial blood flow,positron emission tomography,cardiomyopathy,clinical outcomes,coronary flow reserve,coronary vascular dysfunction

Data availability:

Keywords: myocardial blood flow, positron emission tomography, cardiomyopathy, clinical outcomes, coronary flow reserve, coronary vascular dysfunction

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