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      Mini Asymmetric Radial Keratotomy and Corneal Cross-linking for the Treatment of a Bilateral Stage IV Keratoconus in a 14-year-old Child

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          Abstract

          Aim:

          To present the case of a 14-year-old boy with bilateral stage IV keratoconus, treated with a combined MARK + CXL intervention, without the need for a corneal transplantation.

          Results:

          The left eye displays considerable improvements, with a follow-up of 13.5 years: Kmax is decreased by 5.53 D, Kmed is decreased by 1.95 D and thinnest pachymetry is increased by 106 µm. The right eye shows equally remarkable parameters, with a follow-up of 9.5 years: Kmax is decreased by 8.16 D, Kmed is decreased by 0.38 D and thinnest pachymetry is increased by 52 µm. Keratoconus has been halted and the patient has a binocular best corrected visual acuity of -0.079 LogMAR (12/10).

          Conclusion:

          The MARK + CXL combined intervention, known as the “Rome Protocol”, was successful in halting a bilateral stage IV keratoconus and improving visual acuity in a very young patient, with long-term follow-up. Conservative treatments should always be privileged when treating very young patients with developed stages of the pathology.

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          Most cited references6

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          Correcting keratoconus with intracorneal rings.

          To evaluate the potential of intrastromal corneal ring technology (Intacs, KeraVision) to correct keratoconus without central corneal scarring. Department of Ophthalmology, Brest University Hospital, Brest, France. In this prospective, noncomparative, interventional case series, Intacs segments were implanted in 10 keratoconic eyes with clear central corneas and contact lens intolerance after corneal pachymetry was checked. Segment thicknesses varied based on corneal topography analysis. No intraoperative complications occurred. The mean follow-up was 10.6 months. Postoperative results revealed a reduction in astigmatism and spherical correction and an increase in topographical regularity and increased uncorrected visual acuity. Intacs technology can reduce the corneal steepening and astigmatism associated with keratoconus.
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            Conductive keratoplasty followed by collagen cross-linking with riboflavin-UV-A in patients with keratoconus.

            To evaluate the combined effect of conductive keratoplasty (CK) followed by corneal collagen cross-linking (CXL) in 2 patients with keratoconus.
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              Asymmetric radial keratotomy for the correction of keratoconus.

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                Author and article information

                Journal
                Med Arch
                Med Arch
                Medical Archives
                AVICENA, d.o.o., Sarajevo (Bosnia and Herzegovina )
                0350-199X
                1986-5961
                February 2017
                05 February 2017
                : 71
                : 1
                : 69-71
                Affiliations
                [1 ]Abbondanza Eye Centers, Rome and Milan, Italy
                [2 ]University of Sydney, Sydney (NSW), Australia
                Author notes
                Corresponding author: Marco Abbondanza, MD, Abbondanza Eye Center, Via Luigi Bodio 72, 00191 Roma (RM), Italy. Tel: +39063207111. E-mail: info@ 123456abbondanza.org
                Article
                MA-71-69
                10.5455/medarh.2017.71.69-71
                5364792
                28428679
                28e7645c-83cb-40e0-8512-2dbbd41402eb
                Copyright: © 2017 Marco Abbondanza, Gabriele Abbondanza, Valentina De Felice

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Case Report

                keratoconus,cornea,mini asymmetric radial keratotomy,mark,corneal collagen cross-linking,cxl

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